Evidence map›Paper›PMID 36818774›Full record

ArticleTransfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie2023

Risk Factors and Outcomes of Stem Cell Mobilization Failure in Multiple Myeloma Patients.

Te-Lin Hsu, Chun-Kuang Tsai, Chun-Yu Liu, Chiu-Mei Yeh, Fen-Lan Lin, Liang-Tsai Hsiao, Yao-Chung Liu, Hao-Yuan Wang, Po-Shen Ko, Ting-An Lin and 5 more

Open access · goldAbstract read
In one paragraph

Article in Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Te-Lin HsuDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Chun-Kuang TsaiDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Chun-Yu LiuSchool of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
Chiu-Mei YehDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Fen-Lan LinDivision of Transfusion Medicine, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Liang-Tsai HsiaoDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Yao-Chung LiuDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Hao-Yuan WangDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Po-Shen KoDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Ting-An LinDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Wen-Chun ChenDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Po-Min ChenDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Jin-Hwang LiuInstitute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
Jyh-Pyng GauDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Chia-Jen LiuDivision of Hematology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Autologous hematopoietic stem cell transplantation (ASCT) is a well-established treatment for patients with multiple myeloma (MM), and adequate stem cell collection must be assured before ASCT. However, prediction of poor mobilizers (PMs) is still difficult despite several risk factors for mobilization failure having been identified. Methods: We retrospectively analyzed MM patients at Taipei Veterans General Hospital in Taiwan who underwent stem cell collection between October 2006 and August 2020. A CD34 Results: In the multivariate analysis, absolute monocyte count <500/µL (adjusted OR 10.75, 95% CI: 1.82-63.57, Conclusion: Absolute monocyte count <500/µL, platelet count <150,000/µL, and treatment duration more than 180 days before stem cell mobilization are risk factors for unsuccessful stem cell collection. Our prediction models have high sensitivity and specificity for mobilization failure prediction and allow for early interventions for possible PMs.

Indexed as

Autologous hematopoietic stem cell transplantationMultiple myelomaPoor mobilizersStem cell mobilizationThrombocytopenia

Identifiers

PMID36818774
PMCPMC9912005
OpenAlexW4294653752

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.