Evidence map›Paper›PMID 36818760›Full record

ArticleComputational toxicology (Amsterdam, Netherlands)2022

Principles and Procedures for Assessment of Acute Toxicity Incorporating

Craig M Zwickl, Jessica Graham, Robert Jolly, Arianna Bassan, Ernst Ahlberg, Alexander Amberg, Lennart T Anger, Tara Barton-Maclaren, Lisa Beilke, Phillip Bellion and 33 more

Abstract read
In one paragraph

Article in Computational toxicology (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Therapeutic Potential ofFood science & nutrition · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors.

Craig M ZwicklTransendix LLC, Indianapolis, IN 46229, USA.
Jessica GrahamGenentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Robert JollyEli Lilly and Company, Indianapolis, IN 46285, USA.
Arianna BassanInnovatune srl, Via Giulio Zanon 130/D, 35129 Padova, Italy.
Ernst AhlbergUniversal Prediction AB, Gothenburg, Sweden.
Alexander AmbergSanofi, R&D Preclinical Safety Frankfurt, Industriepark Hoechst, D-65926 Frankfurt am Main, Germany.
Lennart T AngerGenentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Tara Barton-MaclarenHealthy Environments and Consumer Safety Branch, Health Canada / Government of Canada.
Lisa BeilkeToxicology Solutions, Inc., 10531 4S Commons Dr. #594, San Diego, CA 92127, USA.
Phillip BellionBoehringer Ingelheim Animal Health, Binger Str. 128, 55216 Ingelheim am Rhein, Germany.
Alessandro BrigoRoche Pharmaceutical Research & Early Development, Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland.
Mark T D CroninLiverpool John Moores University, Liverpool, L3 3AF, UK.
Laura CusterBristol Myers-Squibb, New Brunswick, NJ, USA.
Amy DevlinFDA Center for Drug Evaluation and Research, Silver Spring, MD 20993, USA.
Heather Burleigh-FlayersPPG Industries, Monroeville, PA 15146, USA.
Trevor FishNelson Laboratories, Salt Lake City, Utah, USA.
Kyle GloverUS Army, DEVCOM Chemical Biological Center.
Susanne GlowienkeNovartis, Basel, Switzerland.
Kamila GromekGlaxo Smith-Kline.
David JonesMHRA, 10 South Colonnade, Canary Wharf, London E14 4PU.
Agnes KarmausIntegrated Laboratory Systems, LLC, Morrisville, NC, USA.
Ray KemperNuvalent, Cambridge, MA 02142, USA.
Elena Lo PiparoChemical Food Safety Group, Nestlé Research, Lausanne, Switzerland.
Federica MadiaEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Matthew MartinPfizer.
Melisa Masuda-HerreraGilead Sciences.
Britt McAteePPG Industries, Monroeville, PA 15146, USA.
Jordi MestreIMIM Institut Hospital Del Mar d'Investigacions Mèdiques and Universitat Pompeu Fabra, Doctor Aiguader 88, Parc de Recerca Biomèdica, 08003 Barcelona, Spain.
Lawrence Milchak3M Company, St. Paul, MN.
Chandrika MoudgalGenentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Moiz MumtazOffice of the Associate Director for Science, Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Wolfgang MusterRoche Pharmaceutical Research & Early Development, Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland.
Louise NeilsonJapan Tobacco International.
Grace PatlewiczCentre for Computational Toxicology and Exposure (CCTE), US Environmental Protection Agency, Research Triangle Park, NC, USA.
Alexandre PaulinoOro Agri Europe, S.A.
Alessandra RoncaglioniLaboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Patricia RuizCenters for Disease Control and Prevention (CDC), Atlanta, GA 30341, USA.
Diana SuarezFSTox Consulting LTD, 2 Brooks Road Raunds Wellingborough NN9 6NS.
David T SzaboPPG Industries, Monroeville, PA 15146, USA.
Jean-Pierre ValentinUCB-Biopharma SRL, Development Science, Avenue de l'industrie, Braine l'Alleud, Wallonia, Belgium.
Ioanna VardakouBritish American Tobacco (Investments) Ltd., R&D Centre, Southampton, Hampshire SO15 8TL, UK.
David WoolleyForthTox Limited, Linlithgow, EH49 7YU, UK.
Glenn MyattInstem, 1393 Dublin Rd, Columbus, OH 43215, USA.

Funding

Rapid response toxicology prediction platformR44ES026909 · NIEHS · LEADSCOPE, INC. · PI MYATT, GLENN JOHN · 2018 to 2019
$1000k
Intramural EPA EPA999999NIEHS NIH HHS R44 ES026909
6 · The paper itself

Abstract

Acute

Identifiers

PMID36818760
PMCPMC9934006

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.