Evidence map›Paper›PMID 36818479›Full record

ReviewAnesthesiology and pain medicine2022

A Multimodal Clinical Approach for the Treatment of Bone Metastases in Solid Tumors.

Giuliano Lo Bianco, Ezio Lanza, Salvatore Provenzano, Manuela Federico, Alfonso Papa, Farnad Imani, Gholamhosein Shirkhany, Riccardo Laudicella, Natale Quartuccio

Open access · diamondAbstract readReview
In one paragraph

Review in Anesthesiology and pain medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. [Pharmaceutics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Giuliano Lo BiancoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Italy.ORCID https://orcid.org/0000-0003-2705-1548
Ezio LanzaDepartment of Radiology, Humanitas Clinical and Research Center - IRCCS, Milan, Italy.ORCID https://orcid.org/0000-0003-1889-8798
Salvatore ProvenzanoCancer Medicine Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.ORCID https://orcid.org/0000-0003-0425-4692
Manuela FedericoCasa di cura Macchiarella, U.O. Radioterapia Oncologica, Palermo, Italy.
Alfonso PapaPain Department, A.O. Dei Colli - V. Monaldi Hospital, Napoli, Italy.ORCID https://orcid.org/0000-0003-4489-714X
Farnad ImaniPain Research Center, Department of Anesthesiology and Pain Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-0814-0772
Gholamhosein ShirkhanyDepartment of Anesthesiology, School of Medicine, Sabzevar University of Medical Sciences, Iran.ORCID https://orcid.org/0000-0001-7990-2979
Riccardo LaudicellaNuclear Medicine Unit, Fondazione Istituto G.Giglio, Cefalù, Italy.ORCID https://orcid.org/0000-0002-2842-0301
Natale QuartuccioNuclear Medicine Unit, A.R.N.A.S. Ospedali Civico, Di Cristina e Benfratelli, Palermo, Italy.ORCID https://orcid.org/0000-0001-9845-1384
Iran University of Medical Sciences · IRAzienda di Rilievo Nazionale ed Alta Specializzazione · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITHumanitas University · ITOspedale Monaldi · ITUniversity of Catania · ITUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Bone metastasis (BM) is a frequent complication of cancer, representing the third most common site of secondary spread in solid cancers behind the lung and liver. Bone metastasis is found in up to 90% of prostate and breast cancer patients. They can cause significant complications, such as pathological fractures and paralysis of the spine, which decrease daily functioning and quality of life (QoL) and worsen prognosis. The growing life expectancy of cancer patients due to improvements in systemic therapies may further increase BM's eventuality and clinical burden in cancer patients. Evidence Acquisition: Four physicians from five different specialties were interviewed and resumed the most relevant literature of the last 20 years focusing on pain treatment in BM patients. Results: Treatment for BM ideally involves various types of specialists and assessments. The disease status and patient background should be considered, requiring holistic care and expertise from various medical specialties. Conclusions: Interventional, nuclear medicine, radiotherapy, and mini-invasive techniques can be safe and effective for relieving pain and modifying health-related QoL in BM patients.

Indexed as

Cancer PainPain ManagementRadiation TherapyRadiometabolic TherapySkeletal Metastasis

Identifiers

PMID36818479
PMCPMC9923334
OpenAlexW4283277661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.