Evidence map›Paper›PMID 36818381›Full record

ArticleJournal of healthcare engineering2023

Self-Healing Supramolecular Hydrogels with Antibacterial Abilities for Wound Healing.

Zhiwu Hong, Lei Wu, Zherui Zhang, Jinpeng Zhang, Huajian Ren, Gefei Wang, Xiuwen Wu, Guosheng Gu, Jianan Ren

Open access · hybridAbstract read
In one paragraph

Article in Journal of healthcare engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 12 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhiwu HongResearch Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, China.ORCID 0000-0001-8249-1349
Lei WuResearch Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, China.
Zherui ZhangResearch Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, China.
Jinpeng ZhangResearch Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, China.
Huajian RenResearch Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, China.ORCID 0000-0002-2205-4072
Gefei WangResearch Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, China.
Xiuwen WuResearch Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, China.ORCID 0000-0002-3813-3867
Guosheng GuResearch Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, China.ORCID 0000-0002-7691-5165
Jianan RenResearch Institute of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, China.ORCID 0000-0002-4697-4762
Nanjing General Hospital of Nanjing Military Command · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing due to skin defects is a growing clinical concern. Especially when infection occurs, it not only leads to impair healing of the wound but even leads to the occurrence of death. In this study, a self-healing supramolecular hydrogel with antibacterial abilities was developed for wound healing. The supramolecular hydrogels inherited excellent self-healing and mechanical properties are produced by the polymerization of N-acryloyl glycinamide monomers which carries a lot of amides. In addition, excellent antibacterial properties are obtained by integrating silver nanoparticles (Ag NPs) into the hydrogels. The resultant hydrogel has a demonstrated ability in superior mechanical properties, including stretchability and self-healing. Also, the good biocompatibility and antibacterial ability have been proven in hydrogels. Besides, the prepared hydrogels were employed as wound dressings to treat skin wounds of animals. It was found that the hydrogels could significantly promote wound repair, including relieving inflammation, promoting collagen deposition, and enhancing angiogenesis. Therefore, such self-healing supramolecular hydrogels with composite functional nanomaterials are expected to be used as new wound dressings in the field of healthcare.

Indexed as

HydrogelsMetal NanoparticlesAnimalsAnti-Bacterial AgentsSilverWound HealingAnti-Bacterial AgentsHydrogelsSilver

Identifiers

PMID36818381
PMCPMC9935882
OpenAlexW4319660285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.