ArticleiScience2023
Integrative analysis of metabolome and transcriptome reveals a dynamic regulatory network of potato tuber pigmentation.
Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 34 citations in OpenAlex.
- Synthesis and multi-target evaluation of 2-(2-phenylethyl)/2,3-styrylchromone derivatives as potential anti-Alzheimer's disease agents.Molecular diversity · 2026Article
- Oral bioavailability property prediction based on task similarity transfer learning.Molecular diversity · 2026Article
- Rapid growth and thematic shifts in mRNA therapeutics research catalyzed by the COVID-19 pandemic.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Transcriptome analysis reveals long noncoding RNAs involved in the tuber anthocyanin synthesis of potato (Solanum tuberosum L.).BMC plant biology · 2026Article
- Combined SMRT and Illumina RNA Sequencing Reveals the Alternative Splicing-Mediated Regulation of Anthocyanin Accumulation in Potato (Plants (Basel, Switzerland) · 2026Article
- Article
- Metabolomic and Transcriptomic Analyses Reveal the Molecular Mechanism of Flower Color Variations inMetabolites · 2025Article
- Integrated multi-omics elucidates StAN1 as a key regulator reprogramming flavonoid partitioning and co-regulatory networks in potato tubers.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Integrative metabolomic and transcriptomic analysis provides insight into the mechanism of pigmentation in potato tuber eyes.BMC plant biology · 2025Article
- Systematic analysis of potato MYB family genes and their potential functions in anthocyanin biosynthesis.Scientific reports · 2025Article
- StMYB308L and its regulatory role in flavonoid biosynthesis pathways in potato.BMC plant biology · 2025Article
- Two tandem R2R3 MYB transcription factor genes cooperatively regulate anthocyanin accumulation in potato tuber flesh.Plant biotechnology journal · 2025Article
- The transcription factor WRKY41-FLAVONOID 3'-HYDROXYLASE module fine-tunes flavonoid metabolism and cold tolerance in potato.Plant physiology · 2025Article
- Transcriptomic and targeted metabolomic analysis identifies genes involved in differential anthocyanin accumulation in potato tubers.Frontiers in plant science · 2025Article
- Transcriptome sequencing and screening of anthocyanin related genes in purple potato tubers (Solanum tuberosum L.).BMC genomics · 2024Article
- Combined Metabolome and Transcriptome Analyses Reveals Anthocyanin Biosynthesis Profiles Between Purple and White Potatoes.International journal of molecular sciences · 2024Article
- Transcriptomic and Metabolic Analysis Reveals Genes and Pathways Associated with Flesh Pigmentation in Potato (Current issues in molecular biology · 2024Article
- Potato Berries as a Valuable Source of Compounds Potentially Applicable in Crop Protection and Pharmaceutical Sectors: A Review.Journal of agricultural and food chemistry · 2024Review
- The Applications of Artificial Intelligence (AI)-Driven Tools in Virus-Like Particles (VLPs) Research.Current microbiology · 2024Review
- Widely Targeted Metabolomics Provides New Insights into Nutritional Profiling and Reveals the Flavonoid Pathway of Pea (Foods (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Potatoes consist of flavonoids that provide health benefits for human consumers. To learn more about how potato tuber flavonoid accumulation and flesh pigmentation are controlled, we analyzed the transcriptomic and metabolomic profile of potato tubers from three colored potato clones at three developmental phases using an integrated approach. From the 72 flavonoids identified in pigmented flesh, differential abundance was noted for anthocyanins, flavonols, and flavones. Weighted gene co-expression network analysis further allowed modules and candidate genes that positively or negatively regulate flavonoid biosynthesis to be identified. Furthermore, an R2R3-MYB repressor StMYB3 and an R3-MYB repressor StMYBATV involved in the modulation of anthocyanin biosynthesis during tuber development were identified. Both StMYB3 and StMYBATV could interact with the cofactor StbHLH1 and repress anthocyanin biosynthesis. Our results indicate a feedback regulatory mechanism of a coordinated MYB activator-repressor network on fine-tuning of potato tuber pigmentation during tuber development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.