Evidence map›Paper›PMID 36817910›Full record

ArticleFrontiers in public health2023

Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage.

Long Ma, Shuo Tian, Hai-Ling Zhang, Jing-Yi Wang, Jia-Wen Wang, Hong-Li Yan, Xu-Guang Hu, Qi Shao, Jia-Ming Guo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Long MaDepartment of Radiation Medicine, College of Naval Medicine, Naval Medical University, Shanghai, China.
Shuo TianDepartment of Biochemistry, College of Pharmacy, Naval Medical University, Shanghai, China.
Hai-Ling ZhangDepartment of Neurology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China.
Jing-Yi WangDepartment of Radiation Medicine, College of Naval Medicine, Naval Medical University, Shanghai, China.
Jia-Wen WangDepartment of Radiation Medicine, College of Naval Medicine, Naval Medical University, Shanghai, China.
Hong-Li YanCenter of Reproductive Medicine, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China.
Xu-Guang HuDepartment of Gastrointestinal Surgery, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China.
Qi ShaoInstitute of Neuroscience, Key Laboratory of Molecular Neurobiology of Ministry of Education and The Collaborative Innovation Center for Brain Science, Naval Medical University, Shanghai, China.
Jia-Ming GuoDepartment of Radiation Medicine, College of Naval Medicine, Naval Medical University, Shanghai, China.
Second Military Medical University · CNChanghai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Excessive doses of electromagnetic radiation pose a negative impact on the central nervous system and lead to mental disorders. Molecular hydrogen can scavenge intracellular hydroxyl radicals, acting as an antioxidant, anti-apoptotic and anti-inflammatory agent. We seek to assess the capability of molecular hydrogen to ameliorate brain damage induced by electromagnetic radiation. Methods: NEMP (nuclear electromagnetic pulse), a subset of electromagnetic pulse with high voltage value that could cause severe brain injury, was applied to this study. Male wild-type rats were divided into four groups: the control group, the H Results: The data from the elevated plus maze and the open field test showed that NEMP exposure elicited anxiety-like behavior in rats, which could be alleviated by H Conclusions: H

Indexed as

Brain InjuriesTranscriptomeAnimalsBrainElectromagnetic PhenomenaHydrogenMaleOxidative StressRatsHydrogenelectromagnetic radiationglutathionemetabolomicsmolecular hydrogennuclear electromagnetic pulseradioprotectanttranscriptomics

Identifiers

PMID36817910
PMCPMC9929151
OpenAlexW4318833361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.