ArticleFrontiers in medicine2023
Increased ICU mortality in septic shock patients with hypo- or hyper- serum osmolarity: A retrospective study.
Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Calculated serum osmolarity distribution in critically ill patients with acute pancreatitis: a retrospective cohort study.BMC gastroenterology · 2026Article
- Elevated serum osmolarity is associated with 28-day all-cause mortality in patients with cardiac arrest.World journal of emergency medicine · 2026Article
- Association between serum osmolality trajectories and mortality in sepsis patients: a retrospective multi-cohort study.European journal of medical research · 2025Article
- Trajectory of serum osmolality changes and 28-day mortality risk in patients with sepsis-associated delirium based on the MIMIC-IV database.Scientific reports · 2025Article
- The U-shaped relationship between serum osmolality and in-hospital mortality in patients with traumatic brain injury: a retrospective study based on the MIMIC-IV database.European journal of medical research · 2025Article
- Association between osmolality trajectories and mortality in patients with sepsis: a group-based trajectory model in large ICU open access databases.Frontiers in medicine · 2025Article
- A dynamic nomogram for predicting 28-day mortality in septic shock: a Chinese retrospective cohort study.PeerJ · 2024Article
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11 authors.
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Abstract
Background: While many factors that are associated with increased mortality in septic shock patients have been identified, the effects of serum osmolarity on the outcomes of ICU patients with septic shock have not yet been studied. Methods: The present study was designed to examine the association of serum osmolarity with ICU 28-day mortality in ICU patients with septic shock. Adult patients diagnosed with septic shock from the MIMIC-IV database were selected in this study. The serum osmolarity was calculated synchronously according to the serum concentrations of Na Results: In the present study, a significant difference was observed between the 28-day mortality of septic shock patients with hypo-osmolarity, hyper-osmolarity, and normal osmolarity (30.8%, 34.9%, and 23.0%, respectively, Conclusion: The serum osmolarity disorder is markedly associated with increased 28-day mortality in septic shock patients.
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