ArticleFrontiers in medicine2023
Non-pharmacological prevention of postoperative delirium by occupational therapy teams: A randomized clinical trial.
Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03704090 (Non-pharmacological Prevention of Postoperative Delirium by Occupational Therapy Teams in Patients Older Than 75 Years Undergoing High-risk Elective Surgery), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Non-pharmacological Prevention of Postoperative Delirium by Occupational Therapy Teams in Patients Older Than 75 Years Undergoing High-risk Elective Surgery
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients.The Cochrane database of systematic reviews · 2021Pooled it
- Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients.The Cochrane database of systematic reviews · 2021Pooled it
- Occupational Therapy as Integral Partner in Lower Limb Amputation Rehabilitation: A Clinical Commentary.Occupational therapy in health care · 2026Article
- Evaluation of a Multidimensional Occupational Therapy Environmental Checklist for People Experiencing Delirium During Hospital Admission: A Quasi-Experimental Study.Australasian journal on ageing · 2026Article
- The interrelationship between multiple long-term conditions (MLTC) and delirium: a scoping review.Age and ageing · 2024Article
- Incidence and risk factors of postoperative delirium following hepatic resection: a retrospective national inpatient sample database study.BMC surgery · 2024Article
- Effect of occupational therapy on the occurrence of delirium in critically ill patients: a systematic review and meta-analysis.Frontiers in neurology · 2024Review
- The Association of Infection with Delirium in the Post-Operative Period after Elective CABG Surgery.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Patients who develop postoperative delirium (POD) have several clinical complications, such as increased morbidity, increased hospital stays, higher hospital costs, cognitive and functional impairment, and higher mortality. POD is a clinical condition preventable by standard non-pharmacological measures An intensive Occupational Therapy (OT) intervention has been shown to be highly effective in preventing delirium in critically ill medical patients, but it is unknown the effect in surgical patients. Thus, we designed a prospective clinical study with the aim to determine whether patients undergoing intervention by the OT team have a lower incidence of POD compared to the group treated only with standard measures. Methods: A multicenter, single-blind, randomized clinical trial was conducted between October 2018 and April 2021, in Santiago of Chile, at a university hospital and at a public hospital. Patients older than 75 years undergoing elective major surgery were eligible for the trial inclusion. Patients with cognitive impairment, severe communication disorder and cultural language limitation, delirium at admission or before surgery, and enrolled in another study were excluded. The intervention consisted of OT therapy twice a day plus standard internationally recommended non-pharmacological prevention intervention during 5 days after surgery. Our primary outcome was development of delirium and postoperative subsyndromal delirium. Results: In total 160 patients were studied. In the interventional group, treated with an intensive prevention by OT, nine patients (12.9%) developed delirium after surgery and in the control group four patients (5.5%) [ Discussion: Patients undergoing intervention by the OT team did not have a lower incidence of POD compared to the group treated only with standard non-pharmacological measures in adults older than 75 years who went for major surgery. Clinical trial registration: www.ClinicalTrials.gov, identifier NCT03704090.
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