Evidence map›Paper›PMID 36817723›Full record

ArticleMolecular therapy. Nucleic acids2023

Aptamer-programmable adeno-associated viral vectors as a novel platform for cell-specific gene transfer.

Francesco Puzzo, Chuanling Zhang, Bethany Powell Gray, Feijie Zhang, Bruce A Sullenger, Mark A Kay

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Tissue-specific gene delivery approaches.Bioengineering & translational medicine · 2026
    Review
  6. An Expanded Toolbox for Versatile Chemical Editing of Adeno-Associated Virus.Angewandte Chemie (International ed. in English) · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Therapeutic Applications of Poly-miRNAs and miRNA Sponges.International journal of molecular sciences · 2025
    Review
  15. The deLIVERed promises of gene therapy: Past, present, and future of liver-directed gene therapy.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Potential Targeting Mechanisms for Bone-Directed Therapies.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Francesco PuzzoDepartments of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA.
Chuanling ZhangDepartments of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA.
Bethany Powell GrayDepartment of Surgery, Duke University School of Medicine, Durham, NC 27705, USA.
Feijie ZhangDepartments of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA.
Bruce A SullengerDepartment of Surgery, Duke University School of Medicine, Durham, NC 27705, USA.
Mark A KayDepartments of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA.
Pediatrics and Genetics · USDuke University · USPeking University · CN

Funding

Selection of New rAAV Vectors Using Replicating Viral Capsids LibrariesR01AI116698 · NIAID · STANFORD UNIVERSITY · PI Mark A Kay · 2015 to 2026
$8.0M
OneView 4kX4k sCMOS camera for transmission electron microscopy applicationsS10OD028536 · OD · STANFORD UNIVERSITY · PI MULHOLLAND, JONATHAN W · 2020 to 2020
$195k
NIAID NIH HHS R01 AI116698NIH HHS S10 OD028536
6 · The paper itself

Abstract

Adeno-associated viruses (AAVs) are commonly used for

Indexed as

adeno-associated virusaptamersgene therapyMT: Delivery Strategiesprecision medicinesynthetic biologyvector engineering

Identifiers

PMID36817723
PMCPMC9929486
OpenAlexW4317597443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.