ArticleArchives of medical science : AMS2023
Extended application of BACs-on-Beads technique in prenatal diagnosis.
Article in Archives of medical science : AMS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Wound healing by enhancing cell proliferation: a thermoreversible formulation containing raloxifene.Cell and tissue banking · 2025Article
- Integration of molecular diagnostics and karyotyping for enhanced detection of chromosomal abnormalities in fetuses.Archives of medical science : AMS · 2025Article
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Authors and funding
4 authors.
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Abstract
Introduction: This study explored the application of bacterial artificial chromosomes (BACs)-on-Beads (BoBs) technique, especially its ability to detect microdeletion/microduplication regions with a single probe. Methods: Both chromosome karyotyping and BoBs technique were applied on a total of 2218 pregnant women. Chromosome microarray analysis (CMA) was performed on patients whose cells were reported as being abnormal by BoBs technique with a single probe. Results: Twenty-two cases were detected as microdeletion/microduplication with a single probe, which was consistent with the CMA results. Conclusions: We believe that the microdeletion/microduplication results detected by BoBs technique with a single probe provide comprehensive guidance for prenatal diagnosis.
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