Evidence map›Paper›PMID 36817566›Full record

ArticleJournal of the Belgian Society of Radiology2023

Diffusion-Weighted MRI in the Evaluation of Early-Stage Breast Cancer Treated with a Short Preoperative Radiotherapy: Preliminary Results.

Nathalie Hottat, Jacques Jani, Dominique Badr, Mark De Ridder, André Nazac, Katherina Vanden Houte, Sophie Lecomte, Mieke Cannie

Open access · goldAbstract read
In one paragraph

Article in Journal of the Belgian Society of Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. MR Imaging Features Predictive of Pathologic Complete Response and Survival Outcomes for Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nathalie HottatUniversity Hospital Brugmann, BE.ORCID https://orcid.org/0000-0002-2144-2436
Jacques JaniUniversity Hospital Brugmann, BE.ORCID https://orcid.org/0000-0003-2252-342X
Dominique BadrUniversity Hospital Brugmann, BE.ORCID https://orcid.org/0000-0001-5251-6023
Mark De RidderUZ Brussel, BE.ORCID https://orcid.org/0000-0003-4433-8807
André NazacUniversity Hospital Brugmann, BE.
Katherina Vanden HouteUniversity Hospital Brugmann, BE.ORCID https://orcid.org/0000-0003-2014-6675
Sophie LecomteUniversity Hospital Brugmann, BE.ORCID https://orcid.org/0000-0002-8275-2761
Mieke CannieUniversity Hospital Brugmann, BE.ORCID https://orcid.org/0000-0001-9899-6851
Mathys (Netherlands) · NLCentre Hospitalier Universitaire Brugmann · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess tumor response with diffusion-weighted MRI (DW-MRI) after a short preoperative radiotherapy in early-stage breast cancer (BCa). Materials and Methods: This was a prospective, single-center pilot study. 3T-MRI were performed before and after radiotherapy. The longest diameter (LD) and the apparent diffusion coefficient (ADC) value of a region of interest (ROI) of the tumors were recorded. Histopathology and immunohistochemistry, including the Ki-67 index of the core biopsy and of the surgical specimen, were the reference standards. Results: Nineteen patients with 22 early-stage BCa were included. The mean ROI ADC value was 1.093 ± 0.278 × 10 Conclusion: In early-stage BCa, a significant increase in ROI-ADC at DWI and a significant decrease in Ki-67 index were observed after a short preoperative radiotherapy, suggesting early tumor response.

Indexed as

apparent diffusion coefficientdiffusion-weighted MRIearly-stage breast cancerKi-67 indexneoadjuvant radiotherapy

Identifiers

PMID36817566
PMCPMC9912849
OpenAlexW4319350662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.