Evidence map›Paper›PMID 36817453›Full record

ArticleFrontiers in immunology2023

Chronological changes of viral shedding in adult inpatients with Omicron infection in Shanghai, China.

Xinru Zhou, Xiaochun Huang, Tingting Sun, Xiaolan Jin, Zhaofeng Tian, Miao Xue, Jinsong Kang, Bai Gao, Aijing Xu, Yi Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Xinru ZhouDepartment of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, China.
Xiaochun HuangDepartment of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, China.
Tingting SunDepartment of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, China.
Xiaolan JinDepartment of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, China.
Zhaofeng TianDepartment of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, China.
Miao XueDepartment of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, China.
Jinsong KangDepartment of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, China.
Bai GaoInformation Department, Changhai Hospital, Second Military Medical University, Shanghai, China.
Aijing XuInfectious Department, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yi ChenInfectious Department, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yin JiaDepartment of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, China.
Shanrong LiuDepartment of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, China.
Second Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Coronavirus disease 2019 (COVID-19) caused by the Omicron variant occurred in Shanghai, China, but its clinical characteristics and virology have not been comprehensively described. Methods: This retrospective cohort study included adult inpatients (≥18 years) diagnosed with COVID-19 at Changhai Hospital. Laboratory and clinical data were obtained from electronic medical records to investigate the clinical characteristics of COVID-19 and the variations in the patients' laboratory indexes were examined. Results: The symptoms of COVID-19 caused by the Omicron variant were relatively mild. Upper respiratory tract specimens yielded higher positive detection rates than lower respiratory tract and intestinal specimens. Peak COVID-19 viral load was reached at the time of admission; quantification cycle (Cq) values increased to approximately 35 after 8.54 days. Conclusions: Virus replication and shedding are rapid in Omicron-positive patients; COVID-19 in these patients is characterized by acute onset, mild symptoms, and fast recovery. Older patients and those with more severe disease demonstrate prolonged virus shedding. Routine hematological indexes can reveal disease severity and help clinically evaluate the patient's condition.

Indexed as

COVID-19AdultChinaHumansInpatientsRetrospective StudiesSARS-CoV-2Virus Sheddingcoronavirus disease 2019Omicronquantification cyclesevere acute respiratory syndrome coronavirus 2viral load

Identifiers

PMID36817453
PMCPMC9929285
OpenAlexW4319794970

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.