ArticleCentral-European journal of immunology2022
Immune cell-specific smoking-related expression characteristics are revealed by re-analysis of transcriptomes from the CEDAR cohort.
Article in Central-European journal of immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 7 citations in OpenAlex.
- Smoking-Associated Changes in Gene Expression in Coronary Artery Disease Patients Using Matched Samples.Current issues in molecular biology · 2024Article
- Active and Passive Smoking as Catalysts for Cognitive Impairment in Rural Indonesia: A Population-based Study.Oman medical journal · 2024Article
- Transcriptomic Context ofBiomedicines · 2023Article
- A Macrophage-Related Gene Signature for Identifying COPD Based on Bioinformatics and ex vivo Experiments.Journal of inflammation research · 2023Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
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Abstract
Introduction: Smoking is known to affect whole-blood expression and methylation profiles. Although whole-genome methylation studies indicated that effects observed in blood may be driven by changes within leukocyte subtypes, these phenomena have not been explored using expression profiling. Material and methods: This study reanalyzed data from the Correlated Expression and Disease Association Research (CEDAR) patient cohort recruited by Momozawa et al. (E-MTAB-6667). Data from gene expression profiling of immunomagnetically sorted CD4 Results: Ninety-four differentially expressed genes were found (CD8 Conclusions: Smoking specifically alters vital immune regulation genes in lymphocyte subtypes, especially CD4
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