Evidence map›Paper›PMID 36817226›Full record

ArticleGlobal heart2023

High Dietary Sodium, Measured Using Spot Urine Samples, is Associated with Higher Blood Pressure among Young Adults in Haiti.

Adrienne Clermont, Vanessa Rouzier, Jean Lookens Pierre, Rodney Sufra, Eliezer Dade, Fabyola Preval, Stephano St-Preux, Marie Marcelle Deschamps, Alexandra Apollon, Kathryn Dupnik and 13 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Global heart, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03892265 (A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03892265 active not recruitingnot on this map

A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti

TypeobservationalSponsorWeill Medical College of Cornell UniversityRan2019 to 2028Enrolled3,005ConditionsHypertension, Diabetes, Obesity, Kidney DiseasesArmsObservational Study
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 4 institutions in 2 countries.

Adrienne ClermontCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.ORCID 0000-0002-5608-7593
Vanessa RouzierHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), 33 Boulevard Harry Truman, Port-au-Prince 6110, Haiti.
Jean Lookens PierreHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), 33 Boulevard Harry Truman, Port-au-Prince 6110, Haiti.
Rodney SufraHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), 33 Boulevard Harry Truman, Port-au-Prince 6110, Haiti.
Eliezer DadeHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), 33 Boulevard Harry Truman, Port-au-Prince 6110, Haiti.
Fabyola PrevalHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), 33 Boulevard Harry Truman, Port-au-Prince 6110, Haiti.
Stephano St-PreuxHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), 33 Boulevard Harry Truman, Port-au-Prince 6110, Haiti.
Marie Marcelle DeschampsHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), 33 Boulevard Harry Truman, Port-au-Prince 6110, Haiti.
Alexandra ApollonHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), 33 Boulevard Harry Truman, Port-au-Prince 6110, Haiti.
Kathryn DupnikCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Miranda MetzCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Yanique DuffusCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Shalom SabwaCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Lily D YanCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Myung Hee LeeCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Lawrence G PalmerDepartment of Physiology and Biophysics, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.
Linda M GerberDepartment of Population Health Sciences, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Mark S PeckerDepartment of Medicine, Division of Nephrology and Hypertension, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.
Samuel J MannDepartment of Medicine, Division of Nephrology and Hypertension, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.
Monika M SaffordCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Daniel W FitzgeraldCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Jean W PapeCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Margaret L McNairyCenter for Global Health, Weill Cornell Medicine, 402 East 67th Street, New York, NY 10065, USA.
Gheskio Centers · HTWeill Cornell Medicine · USCenter for Global Health · USCornell University · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
GHESKIO HIV Clinical Trial UnitUM1AI069421 · NIAID · GHESKIO CENTER · PI JEAN WILLIAM PAPE · 2012 to 2026
$23.6M
Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep DisordersR01HL143788 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Margaret Leighton McNairy · 2018 to 2026
$8.9M
Cardiovascular Disease Research Training Program in HaitiD43TW011972 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI Margaret Leighton McNairy, JEAN WILLIAM PAPE · 2021 to 2026
$1.4M
Host susceptibility to Mycobacterium tuberculosis recurrence in HIV-infected peopleK23AI131913 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI DUPNIK, KATHRYN M · 2018 to 2022
$964k
Global Health Research and Training in Cardiovascular DiseaseK24HL163393 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Margaret Leighton McNairy · 2022 to 2026
$604k
FIC NIH HHS D43 TW011972NCATS NIH HHS UL1 TR002384NHLBI NIH HHS K24 HL163393NHLBI NIH HHS R01 HL143788NIAID NIH HHS K23 AI131913NIAID NIH HHS UM1 AI069421
6 · The paper itself

Abstract

Background: Hypertension (HTN) is the leading cardiovascular disease (CVD) risk factor in Haiti and is likely driven by poverty-related social and dietary factors. Salt consumption in Haiti is hypothesized to be high but has never been rigorously quantified. Methods: We used spot urine samples from a subset of participants in the population-based Haiti Cardiovascular Disease Cohort to estimate population mean daily sodium intake. We compared three previously validated formulas for estimating dietary sodium intake using urine sodium, urine creatinine, age, sex, height, and weight. We explored the association between dietary sodium intake and blood pressure, stratified by age group. Results: A total of 1,240 participants had spot urine samples. Median age was 38 years (range 18-93), and 48% were female. The mean dietary sodium intake was 3.5-5.0 g/day across the three estimation methods, with 94.2%-97.9% of participants consuming above the World Health Organization (WHO) recommended maximum of 2 g/day of sodium. Among young adults aged 18-29, increasing salt intake from the lowest quartile of consumption (<3.73 g/day) to the highest quartile (>5.88 g/day) was associated with a mean 8.71 mmHg higher systolic blood pressure (SBP) (95% confidence interval: 3.35, 14.07; p = 0.001). An association was not seen in older age groups. Among participants under age 40, those with SBP ≥120 mmHg consumed 0.5 g/day more sodium than those with SBP <120 mmHg (95% confidence interval: 0.08, 0.69; p = 0.012). Conclusions: Nine out of 10 Haitian adults in our study population consumed more than the WHO recommended maximum for daily sodium intake. In young adults, higher sodium consumption was associated with higher SBP. This represents an inflection point for increased HTN risk early in the life course and points to dietary salt intake as a potential modifiable risk factor for primordial and primary CVD prevention in young adults.

Indexed as

Cardiovascular DiseasesHypertensionSodium, DietaryAdolescentAdultAgedAged, 80 and overBlood PressureFemaleHaitiHumansMaleMiddle AgedSodiumSodium Chloride, DietaryYoung AdultSodiumSodium Chloride, DietarySodium, DietaryHaitihypertensionsalt consumptionspot urine samples

Identifiers

PMID36817226
PMCPMC9936908
OpenAlexW4320726962

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.