ArticleJCPP advances2022
Attention-deficit/hyperactivity disorder and white matter microstructure: the importance of dimensional analyses and sex differences.
Article in JCPP advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 6 citations in OpenAlex.
- Interrogating cognitive and neural group variation in childhood: Examples in adolescent brain cognitive development and Oregon attention-deficit/hyperactivity disorder-1000 cohorts.Journal of psychopathology and clinical science · 2026Article
- White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy.Annals of clinical and translational neurology · 2026Article
- Associations between cerebellum and major psychiatric disorders: a bidirectional Mendelian randomization study.European archives of psychiatry and clinical neuroscience · 2026Article
- Involvement of the Cerebellar Peduncles inInternational journal of molecular sciences · 2025Review
- A mathematical framework for modelling the dynamic nature of ADHD symptoms.Frontiers in psychiatry · 2025Article
- A preliminary study of white matter correlates of a laboratory measure of attention and motor stability in attention-deficit/hyperactivity disorder.Journal of psychiatric research · 2023Article
- Attention-deficit/hyperactivity disorder and white matter microstructure: the importance of dimensional analyses and sex differences.JCPP advances · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Background: Attention-deficit/hyperactive disorder (ADHD) has substantial heterogeneity in clinical presentation. A potentially important clue may be variation in brain microstructure. Using fractional anisotropy (FA), previous studies have produced equivocal results in relation to ADHD. This may be due to insufficient consideration of possible sex differences and ADHD's multi-componential nature. Methods: Using whole-brain analyses, we investigated the association between FA and both ADHD diagnosis and ADHD symptom domains in a well-characterized, ADHD (n = 234; 32% female youth) and non-ADHD (n = 177; 52% female youth), case-control cohort (ages 7-12). Sex-specific effects were tested. Results: No ADHD group differences were found using categorical assessment of ADHD without consideration of moderators. However, dimensional analyses found total symptoms were associated with higher FA in the superior corona radiata. Further, Conclusions: ADHD symptom domains appear to be differentially related to white matter microstructure, highlighting the multi-componential nature of the disorder. Further, sex differences will be crucial to consider in future studies characterizing ADHD-related differences in white matter microstructure.
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