Evidence map›Paper›PMID 36817139›Full record

ArticleFrontiers in pharmacology2023

Celastrol inhibits store operated calcium entry and suppresses psoriasis.

Xiaoman Yuan, Bin Tang, Yilan Chen, Lijuan Zhou, Jingwen Deng, Lin Han, Yonggong Zhai, Yandong Zhou, Donald L Gill, Chuanjian Lu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. CRAC channels as targets for immunotherapy.Current opinion in immunology · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. The role of celastrol in inflammation and diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. ORAI CaBiomolecules · 2024
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Xiaoman YuanBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Bin TangState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Yilan ChenBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Lijuan ZhouBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Jingwen DengState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Lin HanState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Yonggong ZhaiBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Yandong ZhouDepartment of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, PA, United States.
Donald L GillDepartment of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, PA, United States.
Chuanjian LuState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Youjun WangBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China.
Beijing Normal University · CNGuangzhou University of Chinese Medicine · CNPennsylvania State University · US

Funding

Understanding Store-Operated Calcium Signal TransductionR35GM131916 · NIGMS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI GILL, DONALD L · 2019 to 2023
$2.9M
NIGMS NIH HHS R35 GM131916
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

calciumcelastrolCRAC channelOrai1psoriasisSOCESTIM1

Identifiers

PMID36817139
PMCPMC9928759
OpenAlexW4318815047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.