ArticleACS omega2023
Attenuation of Lipopolysaccharide-Induced Inflammatory Responses through Inhibition of the NF-κB Pathway and the Increased NRF2 Level by a Flavonol-Enriched
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Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40citing papers in PubMed
11.4field-weighted citation impact, top 1% of its field
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Who cites it
40 citing papers in PubMed, 74 citations in OpenAlex.
- From Xenobiotic Exposure to Neuroinflammation: Mechanisms Linking Lipopolysaccharide Signaling to Depressive-like Behavior.Journal of xenobiotics · 2026Review
- Structure-Activity Relationship of Flavonol O-Methylation Revealed by In Vitro, In Silico and Zebrafish Neurodegeneration Models.International journal of molecular sciences · 2026Article
- Archidendron clypearia extract ameliorates dextran sulfate sodium-induced colitis in mice and modulates gut microbiota composition.Archives of microbiology · 2026Article
- Anti-Inflammatory Activity ofPharmaceuticals (Basel, Switzerland) · 2026Article
- A dihydrofuro[2,3-b] benzofuran derivative alleviates lipopolysaccharide induced acute lung injuryFrontiers in pharmacology · 2026Article
- Medicinal Plants That Modulate Nitric Oxide Synthase Activity: Implications in Inflammation and Oxidative Stress.Drug design, development and therapy · 2026Review
- Anti-Inflammatory Effects of Stachys pilifera Extracts in LPS-Stimulated RAW264.7 Macrophages.Mediators of inflammation · 2026Article
- Modulation of the KEAP1-NRF2 pathway by Erianin: A novel approach to reduce psoriasiform inflammation and inflammatory signaling.Open life sciences · 2025Article
- Anti-inflammatory effects of Frondanol, a nutraceutical extract fromFrontiers in pharmacology · 2025Article
- Secondary metabolites of Alternaria alternate appraisal of their SARS-CoV-2 inhibitory and anti-inflammatory potentials.PloS one · 2025Article
- Cooling Blood and Detoxicating Formula Treats Psoriasis Through RHCG-Related Mechanisms.International journal of genomics · 2025Article
- Anti-inflammatory mechanism of total flavonoids fromFrontiers in immunology · 2025Article
- Network Pharmacology Analysis andCombinatorial chemistry & high throughput screening · 2025Article
- The Role of Zuo Jin Wan in Modulating the Tumor Microenvironment of Colorectal Cancer.Combinatorial chemistry & high throughput screening · 2025Article
- Matrine: A Promising Treatment for Ulcerative Colitis by Targeting the HMGB1/NLRP3/Caspase-1 Pathway.Combinatorial chemistry & high throughput screening · 2025Article
- Alleviating Acute Lung Injury Induced by Lipopolysaccharide: Dayuan Yin Suppresses Inflammation and Oxidative Stress in Elderly Male Rats.Combinatorial chemistry & high throughput screening · 2025Article
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- Bushen Zhuyun Decoction Improves Endometrial Receptivity by Inhibiting NF-κB/NLRP3 Signaling Pathway.Combinatorial chemistry & high throughput screening · 2025Article
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- Network Pharmacology and Experimental Validation of Jinwei Decoction for Enhancement of Glucocorticoid Anti-Inflammatory Effect in COPD through miR-155-5p.Combinatorial chemistry & high throughput screening · 2025Article
Corrections and comments
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Authors and funding
17 authors at 9 institutions in 6 countries.
Kin Israel R NotarteLaboratory of Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for Natural and Applied Sciences, University of Santo Tomas, España, 1015Manila, Philippines.ORCID https://orcid.org/0000-0002-6055-0886
Mark Tristan J QuimqueLaboratory of Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for Natural and Applied Sciences, University of Santo Tomas, España, 1015Manila, Philippines.ORCID https://orcid.org/0000-0003-0269-5590
Imee T MacaranasFaculty of Medicine and Surgery, University of Santo Tomas, España, 1008Manila, Philippines.
Abbas KhanDepartment of Bioinformatics and Biostatistics, State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, 800 Dongchuan Road Shanghai, Minhang District, Shanghai200240, China.ORCID https://orcid.org/0000-0002-4288-7602
Adriel M PastranaFaculty of Medicine and Surgery, University of Santo Tomas, España, 1008Manila, Philippines.
Oliver B VillafloresLaboratory of Phytochemistry, Research Center for Natural and Applied Sciences, University of Santo Tomas, España, 1015Manila, Philippines.ORCID https://orcid.org/0000-0002-3437-9130
Hans Christian P ArturoLaboratory of Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for Natural and Applied Sciences, University of Santo Tomas, España, 1015Manila, Philippines.
Delfin Yñigo H Pilapil IvLaboratory of Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for Natural and Applied Sciences, University of Santo Tomas, España, 1015Manila, Philippines.ORCID https://orcid.org/0000-0002-9156-8587
Sophia Morgan M TanLaboratory of Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for Natural and Applied Sciences, University of Santo Tomas, España, 1015Manila, Philippines.
Dong-Qing WeiDepartment of Bioinformatics and Biostatistics, State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, 800 Dongchuan Road Shanghai, Minhang District, Shanghai200240, China.ORCID https://orcid.org/0000-0003-4200-7502
Arlette Wenzel-StorjohannGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Product Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, 24106Kiel, Germany.
Deniz TasdemirGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Product Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, 24106Kiel, Germany.ORCID https://orcid.org/0000-0002-7841-6271
Chia-Hung YenNational Natural Product Libraries and High-Throughput Screening Core Facility, Kaohsiung Medical University, Kaohsiung80708, Taiwan.ORCID https://orcid.org/0000-0002-6939-5528
Seon Yeong JiDepartment of Biochemistry, Dongeui University College of Korean Medicine, 52-57, Yangjeong-ro, Busanjin-gu, Busan47227Republic of Korea.
Gi-Young KimDepartment of Marine Life Science, Jeju National University, 102 Jejudaehak-ro, Jeju-si, Jeju Special Self-Governing Province63243, Republic of Korea.ORCID https://orcid.org/0000-0002-6878-0790
Yung Hyun ChoiDepartment of Biochemistry, Dongeui University College of Korean Medicine, 52-57, Yangjeong-ro, Busanjin-gu, Busan47227Republic of Korea.
Allan Patrick G MacabeoLaboratory of Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for Natural and Applied Sciences, University of Santo Tomas, España, 1015Manila, Philippines.ORCID https://orcid.org/0000-0001-7972-106X
University of Santo Tomas · PHDong-Eui University · KRShanghai Jiao Tong University · CNChristian-Albrechts-Universität zu Kiel · DEGEOMAR Helmholtz Centre for Ocean Research Kiel · DEJeju National University · KRJohns Hopkins University · USKaohsiung Medical University · TWMindanao State University – Iligan Institute of Technology · PH
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathologic hyperreactive inflammatory responses occur when there is excessive activation of a proinflammatory NF-κB pathway and a reduced cytoprotective NRF2 cascade. The noncytotoxic, highly selective COX-2 inhibitory flavonol-enriched butanol fraction (UaB) from
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.