Evidence map›Paper›PMID 36816667›Full record

ArticleACS omega2023

LncRNA-GAS5 and β-Catenin as Independent Predictors of Asymptomatic Organ Damage in Nondiabetic Hypertensive Patients.

Marwa M Esawy, Amir Abd-Elhameed, Ahmed F Gomaa, Shereen A Baioumy, Moataz A ElKot, Mohammed A Hegab, Ahmed S Alazzouni, Felwa A Thagfan, Rewaida Abdel-Gaber, Mohamed A Dkhil and 1 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. LncRNA BACE1-AS delays the propagation ofMicrobiology spectrum · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Marwa M EsawyClinical Pathology Depart, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt.
Amir Abd-ElhameedInternal Medicine Department, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt.
Ahmed F GomaaInternal Medicine Department, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt.
Shereen A BaioumyMicrobiology and Immunology Department, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt.
Moataz A ElKotCardiology Department, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt.
Mohammed A HegabOphthalmology Department, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt.
Ahmed S AlazzouniDepartment of Zoology and Entomology, Faculty of Science, Helwan University, Cairo 11795, Egypt.ORCID https://orcid.org/0000-0002-3392-802X
Felwa A ThagfanDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
Rewaida Abdel-GaberDepartment of Zoology, Faculty of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Mohamed A DkhilDepartment of Zoology and Entomology, Faculty of Science, Helwan University, Cairo 11795, Egypt.
Marwa A ShabanaClinical Pathology Depart, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt.
Zagazig University · EGApplied Science Private University · JOHelwan University · EGKing Saud University · SAPrincess Nourah bint Abdulrahman University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is a serious medical condition that can increase the risk of developing heart, brain, kidney, and other diseases. Many asymptomatic hypertension patients experience asymptomatic organ damage (AOD). The purpose of this study was to determine the roles of LncRNA-GAS5 and β-catenin in predicting AOD in hypertensive nondiabetic patients. This study included 256 subjects, 128 hypertension patients (75 of whom had AOD, and 53 of whom did not) and 128 healthy controls. qRT-PCR was used to assess LncRNA-GAS5, and ELISA was used to assess β-catenin. The LncRNA-GAS5 expression level was decreased in hypertensive patients compared to controls (

Identifiers

PMID36816667
PMCPMC9933191
OpenAlexW4318763668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.