Evidence map›Paper›PMID 36816623›Full record

ReviewWorld journal of gastroenterology2023

Liver involvement in patients with COVID-19 infection: A comprehensive overview of diagnostic imaging features.

Davide Ippolito, Cesare Maino, Federica Vernuccio, Roberto Cannella, Riccardo Inchingolo, Michele Dezio, Riccardo Faletti, Pietro Andrea Bonaffini, Marco Gatti, Sandro Sironi

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. COVID-19 Infection, Drugs, and Liver Injury.Journal of clinical medicine · 2025
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Davide IppolitoMilano Bicocca School of Medicine and Surgery, Milano 20126, Italy.
Cesare MainoFondazione IRCCS San Gerardo dei Tintori, Monza 20900, Italy.
Federica VernuccioInstitute of Radiology (DIMED), University Hospital of Padova, Padova 35128, Italy.
Roberto CannellaSection of Radiology-Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, Palermo 90127, Italy.
Riccardo InchingoloDivision of Interventional Radiology, Department of Radiology, Madonna delle Grazie Hospital, Matera 75100, Italy.
Michele DezioDivision of Interventional Radiology, Department of Radiology, Madonna delle Grazie Hospital, Matera 75100, Italy.
Riccardo FalettiDepartment of Surgical Sciences, University of Turin, Turin 10126, Italy.
Pietro Andrea BonaffiniMilano Bicocca School of Medicine and Surgery, Milano 20126, Italy.
Marco GattiDepartment of Diagnostic Radiology, University of Turin, Turin 10126, Italy.
Sandro SironiMilano Bicocca School of Medicine and Surgery, Milano 20126, Italy.
Ospedale Madonna Delle Grazie · ITUniversity of Milano-Bicocca · ITUniversity of Turin · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITOspedale Papa Giovanni XXIII · ITUniversity of Padua · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the first wave of the pandemic, coronavirus disease 2019 (COVID-19) infection has been considered mainly as a pulmonary infection. However, different clinical and radiological manifestations were observed over time, including involvement of abdominal organs. Nowadays, the liver is considered one of the main affected abdominal organs. Hepatic involvement may be caused by either a direct damage by the virus or an indirect damage related to COVID-19 induced thrombosis or to the use of different drugs. After clinical assessment, radiology plays a key role in the evaluation of liver involvement. Ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI) may be used to evaluate liver involvement. US is widely available and it is considered the first-line technique to assess liver involvement in COVID-19 infection, in particular liver steatosis and portal-vein thrombosis. CT and MRI are used as second- and third-line techniques, respectively, considering their higher sensitivity and specificity compared to US for assessment of both parenchyma and vascularization. This review aims to the spectrum of COVID-19 liver involvement and the most common imaging features of COVID-19 liver damage.

Indexed as

COVID-19Liver DiseasesThrombosisCOVID-19 TestingHumansRadiographyAdultsBiliary tract diseasesCOVID-19Fatty liverHepatic infarctionHepatomegalyInfectionLiverLiver diseasesLiver failureMagnetic resonance imagingPediatricsSARS-CoV-2UltrasonographyX-Ray computed tomography

Identifiers

PMID36816623
PMCPMC9932422
OpenAlexW4318981219

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.