Evidence map›Paper›PMID 36816618›Full record

ArticleWorld journal of gastroenterology2023

Caroline Valibouze, Silvia Speca, Caroline Dubuquoy, Florian Mourey, Lena M'Ba, Lucil Schneider, Marie Titecat, Benoît Foligné, Michaël Genin, Christel Neut and 2 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Probiotics: Shaping the gut immunological responses.World journal of gastroenterology · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Caroline ValibouzeDepartment of Digestive Surgery and Transplantation, Lille University Hospital, Lille 59037, France.
Silvia SpecaU1286 - INFINITE - Institute for Translational Research in Inflammation, Univ. Lille, Inserm, CHU Lille, Lille 59000, France.
Caroline DubuquoyIntestinal Biotech Development, Lille 59045, France.
Florian MoureyDepartment of Research and Applications, Gnosis by Lesaffre, Lesaffre Group, Marcq-en-Baroeul 59700, France.
Lena M'BaDepartment of Digestive Surgery and Transplantation, Lille University Hospital, Lille 59037, France.
Lucil SchneiderDepartment of Digestive Surgery and Transplantation, Lille University Hospital, Lille 59037, France.
Marie TitecatU1286 - INFINITE - Institute for Translational Research in Inflammation, Univ. Lille, Inserm, CHU Lille, Lille 59000, France.
Benoît FolignéU1286 - INFINITE - Institute for Translational Research in Inflammation, Univ. Lille, Inserm, CHU Lille, Lille 59000, France.
Michaël GeninULR 2694 - METRICS: Évaluation des Technologies de Santé et des Pratiques Médicales, University of Lille, Lille University Hospital, Lille 59000, France.
Christel NeutU1286 - INFINITE - Institute for Translational Research in Inflammation, Univ. Lille, Inserm, CHU Lille, Lille 59000, France.
Philippe ZerbibDepartment of Digestive Surgery and Transplantation, Lille University Hospital, Lille 59037, France.
Pierre DesreumauxU1286 - INFINITE - Institute for Translational Research in Inflammation, Univ. Lille, Inserm, CHU Lille, Lille 59000, France.
Centre Hospitalier Universitaire de Lille · FRLille Inflammation Research International Center · FREvaluation des technologies de santé et des pratiques médicalesInstitute for Translational Research in InflammationLesaffre (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative recurrence (POR) after ileocecal resection (ICR) affects most Crohn's disease patients within 3-5 years after surgery. Adherent-invasive

aimTo evaluate the efficacy of CNCM I-3856 in preventing POR induced by LF82 in an HLA-B27 transgenic (TgB27) rat model.

methodsSixty-four rats [strain F344, 38 TgB27, 26 control non-Tg (nTg)] underwent an ICR at the 12

resultsnTg animals did not develop POR. A total of 7/8 (87%) of the TgB27 rats receiving LF82 alone had POR (macroscopic score ≥ 2), which was significantly prevented by CNCM I-3856 administration [6/18 (33%) TgB27 rats,

conclusionIn a reliable model of POR induced by LF82 in TgB27 rats, CNCM I-3856 prevents macroscopic POR by decreasing LF82 infection and gut inflammation.

Indexed as

Crohn DiseaseEscherichia coli InfectionsAnimalsBacterial AdhesionEscherichia coliHLA-B27 AntigenIntestinal MucosaRatsRats, Inbred F344Rats, TransgenicSaccharomyces cerevisiaeSulfonamidesHLA-B27 AntigenSulfonamidesW 12Colorectal surgeryCrohn's diseaseEscherichia coliProbioticRecurrenceSaccharomyces cerevisiae

Identifiers

PMID36816618
PMCPMC9932430
OpenAlexW4318980733

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.