Evidence map›Paper›PMID 36816579›Full record

ArticleFrontiers in cellular and infection microbiology2023

4-Allyl-2-methoxyphenol modulates the expression of genes involved in efflux pump, biofilm formation and sterol biosynthesis in azole resistant

Pooja Sen, Lovely Gupta, Mukund Vijay, Maansi Vermani Sarin, Jata Shankar, Saif Hameed, Pooja Vijayaraghavan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Understanding multi-azole resistance inFrontiers in fungal biology · 2026
    Article
  4. Mycology · 2025
    Article
  5. Article
  6. IntegratingCurrent research in microbial sciences · 2024
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pooja SenAnti-mycotic Drug Susceptibility Laboratory, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida, India.
Lovely GuptaAnti-mycotic Drug Susceptibility Laboratory, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida, India.
Mukund VijayAnti-mycotic Drug Susceptibility Laboratory, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida, India.
Maansi Vermani SarinAnti-mycotic Drug Susceptibility Laboratory, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida, India.
Jata ShankarDepartment of Biotechnology and Bioinformatics, Jaypee University of Information Technology, Solan, India.
Saif HameedAmity Institute of Biotechnology, Amity University Haryana, Gurugram (Manesar), India.
Pooja VijayaraghavanAnti-mycotic Drug Susceptibility Laboratory, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida, India.
Amity University · INJaypee University of Information Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Antifungal therapy for aspergillosis is becoming problematic because of the toxicity of currently available drugs, biofilm formation on host surface, and increasing prevalence of azole resistance in Methods: Soil samples were collected from agricultural fields across India; azole-resistant Results: Out of 89 Conclusions: Our results demonstrate that eugenol effects the expression of efflux pump and biofilm associated genes as well as inhibits biofilm formation in azole resistant isolates of

Indexed as

Aspergillus fumigatusAzolesAntifungal AgentsBiofilmsDrug Resistance, FungalEugenolGuaiacolMicrobial Sensitivity TestsSterolsAntifungal AgentsAzolesEugenolGuaiacolSterols4-allyl-2-methoxyphenolAzole-resistant Aspergillus fumigatusbiofilmsMDR4mfsC

Identifiers

PMID36816579
PMCPMC9929553
OpenAlexW4318779525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.