Evidence map›Paper›PMID 36816394›Full record

ArticleContemporary oncology (Poznan, Poland)2022

Assessment of lipid peroxidation status in the serum of Moroccan patients with nasopharyngeal carcinoma.

Gihbid Amina, Debbarh Hasnae, El-Alami Imane, Khaali Wafa, Tawfiq Nezha, Benchakroun Nadia, Benider Abdellatif, Belghmi Khalid, Mzibri Mohammed, Cadi Rachida and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary oncology (Poznan, Poland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Gihbid AminaLaboratory of Pathophysiology, Molecular Genetics, and Biotechnology, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco.
Debbarh HasnaeLaboratory of Pathophysiology, Molecular Genetics, and Biotechnology, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco.
El-Alami ImaneOncovirology Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.
Khaali WafaOncovirology Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.
Tawfiq NezhaRadiotherapy-Oncology Department, Mohammed VI Centre for Treatment of Cancer, Ibn Rochd Hospital Center, Casablanca, Morocco.
Benchakroun NadiaRadiotherapy-Oncology Department, Mohammed VI Centre for Treatment of Cancer, Ibn Rochd Hospital Center, Casablanca, Morocco.
Benider AbdellatifRadiotherapy-Oncology Department, Mohammed VI Centre for Treatment of Cancer, Ibn Rochd Hospital Center, Casablanca, Morocco.
Belghmi KhalidLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco.
Mzibri MohammedBiology and Medical Research Unit, National Centre of Energy, Sciences, and Nuclear Techniques, Rabat, Morocco.
Cadi RachidaLaboratory of Pathophysiology, Molecular Genetics, and Biotechnology, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco.
Khyatti MeriemOncovirology Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.
Institut Pasteur du Maroc · MACentre Hospitalier Universitaire Ibn Rochd · MAUniversity of Hassan II Casablanca · MANational Centre for Nuclear Energy, Science and Technology · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Many studies have addressed the role of oxidative stress products in the carcinogenesis of nasopharyngeal carcinoma (NPC). The current study aimed to assess malondialdehyde (MDA) levels in the serum of patients with NPC before and after chemo- radiotherapy (CRT), to evaluate its potential role as a biomarker in the management of this disease. Material and methods: A total of 112 patients with newly diagnosed NPC, occurring between January 2017 and February 2019, were enrolled and followed up. The level of MDA was determined by spectrophotometric method. Results: Serum MDA levels in NPC patients before CRT were higher (0.911 µmol/ml/mg) than that obtained in the control group (0.613 µmol/ml/mg) ( Conclusions: In conclusion, high levels of MDA in the serum of patients with NPC before CRT, and their increase with disease stage, accurately reflect the heightened oxidative stress level in NPC. These findings strongly imply that MDA serum levels could be used as a biomarker in the progression monitoring of NPC.

Indexed as

biomarkerlipid peroxidationnasopharyngeal carcinomaoxidative stress

Identifiers

PMID36816394
PMCPMC9933355
OpenAlexW4318821364

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.