Evidence map›Paper›PMID 36816319›Full record

ReviewHeliyon2023

A comprehensive review on clinically proven medicinal plants in the treatment of overweight and obesity, with mechanistic insights.

Md Abdul Aziz, Md Shalahuddin Millat, Tahmina Akter, Md Shahadat Hossain, Md Monirul Islam, Shahriar Mohsin, Farzana Ansari, Asma Kabir, Mohammad Nurul Amin, Mohammad Safiqul Islam

Open access · goldAbstract readReview
In one paragraph

Review in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Targeted3 Biotech · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Md Abdul AzizDepartment of Pharmacy, State University of Bangladesh, Dhaka, 1205, Bangladesh.
Md Shalahuddin MillatDepartment of Pharmacy, Noakhali Science and Technology University, Sonapur, 3814, Bangladesh.
Tahmina AkterDepartment of Pharmacy, Noakhali Science and Technology University, Sonapur, 3814, Bangladesh.
Md Shahadat HossainDepartment of Pharmacy, Atish Dipankar University of Science and Technology, Dhaka, 1230, Bangladesh.
Md Monirul IslamDepartment of Pharmacy, State University of Bangladesh, Dhaka, 1205, Bangladesh.
Shahriar MohsinCenter of Molecular Biotechnology, University of Bonn, 53115 Bonn, Germany.
Farzana AnsariDepartment of Biochemistry and Molecular Biology, Laboratory of Nutrition and Health Research, University of Dhaka, Dhaka, 1000, Bangladesh.
Asma KabirDepartment of Pharmacy, Atish Dipankar University of Science and Technology, Dhaka, 1230, Bangladesh.
Mohammad Nurul AminDepartment of Pharmacy, Atish Dipankar University of Science and Technology, Dhaka, 1230, Bangladesh.
Mohammad Safiqul IslamDepartment of Pharmacy, Noakhali Science and Technology University, Sonapur, 3814, Bangladesh.
State University of Bangladesh · BDAtish Dipankar University of Science and Technology · BDNoakhali Science and Technology University · BDUniversity of Bonn · DEUniversity of Dhaka · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: Obesity has become a global health issue, more precisely, a pandemic throughout the present world due to its high prevalence in the recent era. Increased risk of morbidity and mortality in obese patients can be attributed to its association with the development of different life-threatening conditions. Plants are considered one of the most important sources of bioactive molecules which are used against a wide range of health disorders. This systematic review explores the efficacy as well as the safety profile of commonly used medicinal plants in the management of obesity that may help people to maintain a healthy weight. Methods: This review is based on comprehensive literature searches from PubMed, Science Direct, Scopus, and Google Scholar databases using the keywords- "plants in obesity", "plants used in weight reduction" or keywords that are similar to those. Medicinal plants which have been clinically proven for their anti-obesity effect have only been selected for this study and attempts to investigate beneficial effects and adverse effects along with their mechanism of action have also been taken in this review. Results: A significant reduction of weight in both human and other animals are exhibited by the extracts of Phaseolus vulgaris, green coffee, Yerba Mate, green tea, Gynostemma pentaphyllum, and the combination of Cissus quadrangularis/Irvingia gabonensis. All of those plant extracts seemed to work on different physiological pathways and none of those extracts showed any notable adverse effects in human or animal models. Conclusion: Our review suggests that the discussed medicinal plants are effective in reducing the weight of obese patients without causing notable adverse reactions. Although further study is necessary to confirm their exact molecular mechanism and safety in human use.

Indexed as

Cissus quadrangularisGreen coffeeGreen teaGynostemma pentaphyllumIrvingia gabonensisObesityPhaseolus vulgarisWeight lossYerba mate

Identifiers

PMID36816319
PMCPMC9929289
OpenAlexW4319066129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.