Evidence map›Paper›PMID 36815993›Full record

ArticlePeerJ2023

Combined saline and vildagliptin induced M2 macrophage polarization in hepatic injury induced by acute kidney injury.

Shaimaa N Amin, Hader I Sakr, Walaa B El Gazzar, Sherif A Shaltout, Hazem S Ghaith, Dalia A Elberry

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. High-mobility group box 1 in acute kidney injury.Frontiers in pharmacology · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Shaimaa N AminDepartment of Anatomy, Physiology, and Biochemistry, Faculty of Medicine, The Hashemite University, Zarqa, Jordan.
Hader I SakrDepartment of Medical Physiology, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID 0000-0003-2917-2423
Walaa B El GazzarDepartment of Anatomy, Physiology, and Biochemistry, Faculty of Medicine, The Hashemite University, Zarqa, Jordan.
Sherif A ShaltoutDepartment of Pharmacology, Public health, and Clinical Skills, Faculty of Medicine, The Hashemite University, Zarqa, Jordan.
Hazem S GhaithFaculty of Medicine, Al-Azhar University, Cairo, Egypt.ORCID 0000-0002-9519-851X
Dalia A ElberryDepartment of Medical Physiology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Cairo University · EGHashemite University · JOAl-Azhar University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is a prevalent medical condition accompanied by mutual affection of other organs, including the liver resulting in complicated multiorgan malfunction. Macrophages play a vital role during tissue injury and healing; they are categorized into "classically activated macrophages" (M1) and "alternatively activated macrophages" (M2). The present study investigated and compared the conventional fluid therapy

Indexed as

Acute Kidney InjuryTranscription Factor AP-1AnimalsLiverMacrophagesRatsSaline SolutionVildagliptinSaline SolutionTranscription Factor AP-1VildagliptinAcute kidney injuryDipeptidyl peptidase 4 inhibitorLiverMAPK/AP-1Vildagliptin

Identifiers

PMID36815993
PMCPMC9933746
OpenAlexW4320492467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.