Evidence map›Paper›PMID 36815967›Full record

ArticleExperimental and therapeutic medicine2023

Roles of PADI4 in the expression of cytokines involved in inflammation and adhesion in differentiated NB4 cells treated with ATRA.

Xiaobai Sun, Xiao Mu, Fu Li, Yaping Wang, Xiaomei Yang, Qingwei Guo

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaobai SunDepartment of Pathology, Adicon Clinical Laboratory, Jinan, Shandong 250000, P.R. China.
Xiao MuDepartment of Hematology, Children's Hospital Affiliated to Shandong University and Jinan Children's Hospital, Jinan, Shandong 250022, P.R. China.
Fu LiDepartment of Hematology, Children's Hospital Affiliated to Shandong University and Jinan Children's Hospital, Jinan, Shandong 250022, P.R. China.
Yaping WangDepartment of Hematology, Children's Hospital Affiliated to Shandong University and Jinan Children's Hospital, Jinan, Shandong 250022, P.R. China.
Xiaomei YangDepartment of Hematology, Children's Hospital Affiliated to Shandong University and Jinan Children's Hospital, Jinan, Shandong 250022, P.R. China.
Qingwei GuoDepartment of Hematology, Children's Hospital Affiliated to Shandong University and Jinan Children's Hospital, Jinan, Shandong 250022, P.R. China.
Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Differentiation syndrome (DS) is a common complication in patients with acute promyelocytic leukemia (APL) treated with all-trans-retinoic acid (ATRA). However, the target of ATRA during DS in patients with APL remains to be elucidated. Therefore, the current study aimed to investigate the role of peptidylarginine deiminase 4 (PADI4) in the differentiation of ATRA-induced NB4 APL cells. The results showed that PADI4 was significantly upregulated in peripheral blood samples derived from patients with APL DS compared with patients with APL only. In addition, whether ATRA could enhance the expression levels of PADI4 in NB4 cells

Indexed as

acute promyelocytic leukemiadifferentiation syndromepeptidylarginine deiminase 4

Identifiers

PMID36815967
PMCPMC9932641
OpenAlexW4318616780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.