Evidence map›Paper›PMID 36815938›Full record

ArticleInternational journal of clinical and experimental pathology2023

Coexistence of malignancy and tuberculosis: is it double disease or double hit related to COVID-19? - Experience from a tertiary care center.

Subhashini Ramamoorthy, Bheemanathi Hanuman Srinivas, Bhawana Ashok Badhe, Sreerekha Jinkala, Rajesh Nachiappa Ganesh

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Subhashini RamamoorthyDepartment of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) Puducherry-605006, India.
Bheemanathi Hanuman SrinivasDepartment of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) Puducherry-605006, India.
Bhawana Ashok BadheDepartment of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) Puducherry-605006, India.
Sreerekha JinkalaDepartment of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) Puducherry-605006, India.
Rajesh Nachiappa GaneshDepartment of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) Puducherry-605006, India.
Jawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoexistent malignancy and tuberculosis (TB) are rarely encountered. Cancer patients are a highly vulnerable subgroup during this Covid crisis. Delayed treatment for malignancy because of COVID-19 pandemic leads to higher chances to get infections. PURPOSE: The present study aimed to present the clinicopathologic profile of the patients with coexistent carcinoma and TB during the COVID-19 pandemic in a tertiary care center. MATERIALS AND

methodsThis was a retrospective study conducted during the COVID-19 pandemic between April 2020 to May 2021 in the Department of Pathology of our Institute. 11 patients with coexistent malignancy and caseous necrotizing granulomatous inflammation with Langhans giant cells and or acid-fast bacilli (AFB) positivity were included in the study. Cases of ill-defined granulomas coexistent malignancy were excluded. We studied varied clinical and histopathologic features of these cases.

resultsEleven cases were reported with coexistent malignancy and tuberculosis, of which 8 were reported in 2021 and 3 cases were reported in 2020. Adenocarcinoma comprised 9 cases (81.8%) and the remaining 2 were squamous cell carcinoma (18.1%). Out of 11, 10 (90.9%) were new TB cases. Of these, 10 were extrapulmonary TB and one pulmonary TB case with cancer. Regarding chemotherapy, four patients accepted that chemotherapy was delayed because of the COVID-19 crisis.

conclusionIn this covid pandemic, India being the 2

Indexed as

COVID-19Malignancypandemictuberculosis

Identifiers

PMID36815938
PMCPMC9929613
OpenAlexW4321612409

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.