Evidence map›Paper›PMID 36815780›Full record

ArticlemBio2023

Reduced Mortality among COVID-19 ICU Patients after Treatment with HemoClear Convalescent Plasma in Suriname.

R Bihariesingh-Sanchit, R Bansie, N Ramdhani, R Mangroo, D Bustamente, E Diaz, C Fung A Foek, I Thakoer, S Vreden, Z Choudhry and 3 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

R Bihariesingh-SanchitDepartment of Anesthesiology, Academic Hospital Paramaribo, Paramaribo, Suriname.ORCID 0000-0003-0646-9507
R BansieDepartment of Internal Medicine, Academic Hospital Paramaribo, Paramaribo, Suriname.
N RamdhaniDepartment of Anesthesiology, Academic Hospital Paramaribo, Paramaribo, Suriname.
R MangrooDepartment of Internal Medicine, Academic Hospital Paramaribo, Paramaribo, Suriname.
D BustamenteDepartment of Anesthesiology, Academic Hospital Paramaribo, Paramaribo, Suriname.
E DiazDepartment of Intensive Care, Academic Hospital Paramaribo, Paramaribo, Suriname.
C Fung A FoekDepartment of Anesthesiology, Academic Hospital Paramaribo, Paramaribo, Suriname.
I ThakoerDepartment of Radiology, Academic Hospital Paramaribo, Paramaribo, Suriname.
S VredenDepartment of Internal Medicine, Academic Hospital Paramaribo, Paramaribo, Suriname.
Z ChoudhryDepartment of Nephrology and Therapeutic Apheresis, Horacio Oduber Hospital, Oranjestad, Aruba.
A B van 't WoutAlphaBiomics Limited, London, United Kingdom.ORCID 0000-0003-3705-2392
D A DiavatopoulosSection Paediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
A P NierichDepartments of Anesthesiology and Intensive Care, Isala, Zwolle, The Netherlands.
Academic Hospital Paramaribo · SRAstellas Pharma (Netherlands) · NLIsala · NLRadboud University Nijmegen · NLUniversity of Aruba · AW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Convalescent plasma is a promising therapy for coronavirus disease 2019 (COVID-19), but its efficacy in intensive care unit (ICU) patients in low- and middle-income country settings such as Suriname is unknown. Bedside plasma separation using the HemoClear device made convalescent plasma therapy accessible as a treatment option in Suriname. Two hundred patients with severe SARS-CoV-2 infection requiring intensive care were recruited. Fifty eight patients (29%) received COVID-19 convalescent plasma (CCP) treatment in addition to standard of care (SOC). The CCP treatment and SOC groups were matched by age, sex, and disease severity scores. Mortality in the CCP treatment group was significantly lower than that in the SOC group (21% versus 39%; Fisher's exact test

Indexed as

COVID-19COVID-19 SerotherapyCritical CareHumansImmunization, PassiveIntensive Care UnitsSARS-CoV-2SurinameTreatment Outcomeconvalescent plasmaCOVID-19HemoClearICUmortalitySARS-CoV-2

Identifiers

PMID36815780
PMCPMC10127603
OpenAlexW4321611115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.