Evidence map›Paper›PMID 36815680›Full record

ArticleChemical communications (Cambridge, England)2023

Cycloaddition enabled mutational profiling of 5-vinyluridine in RNA.

Mrityunjay Gupta, Jingtian Wang, Chely M Garfio, Abigail Vandewalle, Robert C Spitale

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mrityunjay GuptaDepartment of Chemistry, University of California, Irvine, Irvine, CA 92697, USA. rspitale@uci.edu.ORCID http://orcid.org/0000-0002-9118-1681
Jingtian WangDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697, USA.
Chely M GarfioDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697, USA.
Abigail VandewalleDepartment of Pharmaceutical Sciences, University of California, Irvine, Irvine, CA 92697, USA.
Robert C SpitaleDepartment of Chemistry, University of California, Irvine, Irvine, CA 92697, USA. rspitale@uci.edu.ORCID http://orcid.org/0000-0002-3511-8098

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Shared Resource Core: Single Cell AnalysisU54CA217378 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI SANDMEYER, SUZANNE · 2018 to 2022
$9.7M
UCI P30 Skin Center Systems Biology CoreP30AR075047 · NIAMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LANDER, ARTHUR D · 2019 to 2025
$5.1M
Cracking the RNA Localization CodeDP2GM119164 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SPITALE, ROBERT C · 2015 to 2015
$2.2M
PacBio RS Single Molecule, Real-Time (SMRT) DNA SequencerS10OD010794 · OD · UNIVERSITY OF CALIFORNIA-IRVINE · PI SANDMEYER, SUZANNE · 2012 to 2012
$600k
High-Throughput DNA SequencerS10OD021718 · OD · UNIVERSITY OF CALIFORNIA-IRVINE · PI SANDMEYER, SUZANNE · 2016 to 2016
$600k
High Throughput DNA SequencerS10RR025496 · NCRR · UNIVERSITY OF CALIFORNIA-IRVINE · PI SANDMEYER, SUZANNE · 2009 to 2009
$500k
NCI NIH HHS P30 CA062203NCI NIH HHS U54 CA217378NCRR NIH HHS S10 RR025496NIAMS NIH HHS P30 AR075047NIGMS NIH HHS DP2 GM119164NIH HHS S10 OD010794NIH HHS S10 OD021718
6 · The paper itself

Abstract

We report the detection of 5-vinyluridine (5-VUrd) in RNA at single nucleotide resolution

Indexed as

NucleotidesRNACycloaddition ReactionNucleotidesRNA

Identifiers

PMID36815680
PMCPMC10089805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.