Evidence map›Paper›PMID 36815334›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

The Testing Imperative: Why the US Ending the Human Immunodeficiency Virus (HIV) Epidemic Program Needs to Renew Efforts to Expand HIV Testing in Clinical and Community-Based Settings.

Bohdan Nosyk, Anthony Todd Fojo, Parastu Kasaie, Benjamin Enns, Laura Trigg, Micah Piske, Angela B Hutchinson, Elizabeth A DiNenno, Xiao Zang, Carlos Del Rio

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. The Potential Effect of Ending Centers for Disease Control and Prevention Funding for HIV Tests: A Modeling Study in 18 States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bohdan NosykFaculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Anthony Todd FojoJohns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Parastu KasaieJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Benjamin EnnsHealth Economic Research Unit, Centre for Health Evaluation and Outcome Sciences, Vancouver, British Columbia, Canada.
Laura TriggHealth Economic Research Unit, Centre for Health Evaluation and Outcome Sciences, Vancouver, British Columbia, Canada.
Micah PiskeHealth Economic Research Unit, Centre for Health Evaluation and Outcome Sciences, Vancouver, British Columbia, Canada.
Angela B HutchinsonUS Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Elizabeth A DiNennoUS Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Xiao ZangDepartment of Epidemiology, Brown University School of Public Health, Providence Rhode Island, USA.
Carlos Del RioFaculty of Medicine, Emory University, Atlanta, Georgia, USA.

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Localized economic modeling to support implementation of the Ending the HIV Epidemic initiativeR01DA041747 · NIDA · SIMON FRASER UNIVERSITY · PI NOSYK, BOHDAN · 2016 to 2025
$5.5M
Ending the HIV Epidemic in Rural America (EHE-RA): Local Interventions, Co-Epidemics, and Social DeterminantsR01MD018539 · NIMHD · JOHNS HOPKINS UNIVERSITY · PI Anthony Todd Fojo · 2022 to 2026
$4.0M
Optimizing outcomes at the intersection of HIV and mental health: Prediction, precision medicine, and population healthK08MH118094 · NIMH · JOHNS HOPKINS UNIVERSITY · PI FOJO, ANTHONY TODD · 2018 to 2022
$953k
Projecting the Epidemiologic and Economic Impact of HIV Prevention Efforts in the Context of Other Sexually Transmitted InfectionsK01AI138853 · NIAID · JOHNS HOPKINS UNIVERSITY · PI KASAIE, PARASTU · 2019 to 2023
$591k
NIAID NIH HHS K01 AI138853NIAID NIH HHS P30 AI050409NIDA NIH HHS R01 DA041747NIMHD NIH HHS R01 MD018539NIMH NIH HHS K08 MH118094
6 · The paper itself

Abstract

Data from several modeling studies demonstrate that large-scale increases in human immunodeficiency virus (HIV) testing across settings with a high burden of HIV may produce the largest incidence reductions to support the US Ending the HIV Epidemic (EHE) initiative's goal of reducing new HIV infections 90% by 2030. Despite US Centers for Disease Control and Prevention's recommendations for routine HIV screening within clinical settings and at least yearly screening for individuals most at risk of acquiring HIV, fewer than half of US adults report ever receiving an HIV test. Furthermore, total domestic funding for HIV prevention has remained unchanged between 2013 and 2019. The authors describe the evidence supporting the value of expanded HIV testing, identify challenges in implementation, and present recommendations to address these barriers through approaches at local and federal levels to reach EHE targets.

Indexed as

EpidemicsHIV InfectionsAdultHIVHIV TestingHumansMass ScreeningEnding the HIV EpidemicHIV/AIDSHIV preventionHIV testingsimulation model

Identifiers

PMID36815334
PMCPMC10273343

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.