Evidence map›Paper›PMID 36815248›Full record

ArticleInfection control and hospital epidemiology2023

Risk factors associated with severe acute respiratory coronavirus virus 2 (SARS-CoV-2) transmission, outbreak duration, and mortality in acute-care settings.

Tamara R Duncombe, Matthew Garrod, Xuetao Wang, Joyce Ng, Eunsun Lee, Katy Short, Kennard Tan

Abstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tamara R DuncombeInfection Prevention and Control, Fraser Health, Surrey, British Columbia, Canada.
Matthew GarrodInfection Prevention and Control, Fraser Health, Surrey, British Columbia, Canada.ORCID 0000-0003-4995-7949
Xuetao WangInfection Prevention and Control, Fraser Health, Surrey, British Columbia, Canada.ORCID 0000-0002-1801-5337
Joyce NgInfection Prevention and Control, Fraser Health, Surrey, British Columbia, Canada.
Eunsun LeeInfection Prevention and Control, Fraser Health, Surrey, British Columbia, Canada.
Katy ShortInfection Prevention and Control, Fraser Health, Surrey, British Columbia, Canada.
Kennard TanDepartment of Pathology and Laboratory Medicine, Fraser Health, Surrey, British Columbia, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in acute-care settings affects patients, healthcare workers, and the healthcare system. We conducted an analysis of risk factors associated with outbreak severity to inform prevention strategies.

methodsThis cross-sectional analysis of COVID-19 outbreaks was conducted at Fraser Health acute-care sites between March 2020 and March 2021. Outbreak severity measures included COVID-19 attack rate, outbreak duration, and 30-day case mortality. Generalized linear models with generalized estimating equations were used for all outcome measures. A P value of 0.05 indicated statistical significance. Analyses were performed using SAS version 3.8 software, R version 4.1.0 software, and Stata version 16.0 software.

resultsBetween March 2020 and March 2021, 54 COVID-19 outbreaks were declared in Fraser Health acute-care sites. Overall, a 10% increase in the hand hygiene rate during the outbreak resulted in an 18% decrease in the attack rate (P < .01), 1 fewer death (P = .03), and shorter outbreaks (P < .01). A 10-year increase in unit age was associated with 2.2 additional days of outbreak (P < 0.01) and increases in the attack rate (P < .05) and the number of deaths (P < .01). DISCUSSION: We observed an inverse relationship between increased hand hygiene compliance during outbreaks and all 3 severity measures. Increased unit age was also associated with increases in each of the severity measures.

conclusionThis study highlights the importance of hand hygiene practices during an outbreak and the difficulties faced by older facilities, many of which have infrastructural challenges. The latter reinforces the need to incorporate infection control standards into healthcare planning and construction.

Indexed as

COVID-19Virus DiseasesCross-Sectional StudiesDisease OutbreaksHumansInfant, NewbornMortalityRisk FactorsSARS-CoV-2

Identifiers

PMID36815248
PMCPMC10587374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.