Evidence map›Paper›PMID 36815032›Full record

ArticleActa pharmaceutica Sinica. B2023

Renewal of embryonic and neonatal-derived cardiac-resident macrophages in response to environmental cues abrogated their potential to promote cardiomyocyte proliferation

Rong Chen, Shiqing Zhang, Fang Liu, Lin Xia, Chong Wang, Siamak Sandoghchian Shotorbani, Huaxi Xu, Subrata Chakrabarti, Tianqing Peng, Zhaoliang Su

Open access · diamondAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  8. Maternal Immune Activation: Implications for Congenital Heart Defects.Clinical reviews in allergy & immunology · 2025
    Review
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  12. Macrophage senescence in health and diseases.Acta pharmaceutica Sinica. B · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Rong ChenInternational Genome Center, Jiangsu University, Zhenjiang 212013, China.
Shiqing ZhangInternational Genome Center, Jiangsu University, Zhenjiang 212013, China.
Fang LiuInternational Genome Center, Jiangsu University, Zhenjiang 212013, China.
Lin XiaInternational Genome Center, Jiangsu University, Zhenjiang 212013, China.
Chong WangInternational Genome Center, Jiangsu University, Zhenjiang 212013, China.
Siamak Sandoghchian ShotorbaniDepartment of Immunology, Tabriz University of Medical Sciences, Tabriz 5173957616, Iran.
Huaxi XuInternational Genome Center, Jiangsu University, Zhenjiang 212013, China.
Subrata ChakrabartiLawson Health Research Institute, London Health Sciences Centre, London, Ontario N6A 5W9, Canada.
Tianqing PengLawson Health Research Institute, London Health Sciences Centre, London, Ontario N6A 5W9, Canada.
Zhaoliang SuInternational Genome Center, Jiangsu University, Zhenjiang 212013, China.
Jiangsu University · CNWestern University · CATabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac-resident macrophages (CRMs) play important roles in homeostasis, cardiac function, and remodeling. Although CRMs play critical roles in cardiac regeneration of neonatal mice, their roles are yet to be fully elucidated. Therefore, this study aimed to investigate the dynamic changes of CRMs during cardiac ontogeny and analyze the phenotypic and functional properties of CRMs in the promotion of cardiac regeneration. During mouse cardiac ontogeny, four CRM subsets exist successively: CX

Indexed as

Cardiac injuryCardiac regenerationCardiac resident macrophagesCardiomyocyte proliferationMyocardial infarction

Identifiers

PMID36815032
PMCPMC9939321
OpenAlexW4293565037

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.