Evidence map›Paper›PMID 36814932›Full record

ReviewFrontiers in computational neuroscience2023

Conventional machine learning and deep learning in Alzheimer's disease diagnosis using neuroimaging: A review.

Zhen Zhao, Joon Huang Chuah, Khin Wee Lai, Chee-Onn Chow, Munkhjargal Gochoo, Samiappan Dhanalakshmi, Na Wang, Wei Bao, Xiang Wu

Abstract readReview
In one paragraph

Review in Frontiers in computational neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Feature Integration of [medRxiv : the preprint server for health sciences · 2026
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  14. Transformers for Neuroimage Segmentation: Scoping Review.Journal of medical Internet research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhen ZhaoDepartment of Electrical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Joon Huang ChuahDepartment of Electrical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Khin Wee LaiDepartment of Biomedical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Chee-Onn ChowDepartment of Electrical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Munkhjargal GochooDepartment of Computer Science and Software Engineering, United Arab Emirates University, Al Ain, United Arab Emirates.
Samiappan DhanalakshmiDepartment of Electronics and Communication Engineering, SRM Institute of Science and Technology, Chennai, India.
Na WangSchool of Automation, Guangdong Polytechnic Normal University, Guangzhou, China.
Wei BaoChina Electronics Standardization Institute, Beijing, China.
Xiang WuSchool of Medical Information Engineering, Xuzhou Medical University, Xuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder that causes memory degradation and cognitive function impairment in elderly people. The irreversible and devastating cognitive decline brings large burdens on patients and society. So far, there is no effective treatment that can cure AD, but the process of early-stage AD can slow down. Early and accurate detection is critical for treatment. In recent years, deep-learning-based approaches have achieved great success in Alzheimer's disease diagnosis. The main objective of this paper is to review some popular conventional machine learning methods used for the classification and prediction of AD using Magnetic Resonance Imaging (MRI). The methods reviewed in this paper include support vector machine (SVM), random forest (RF), convolutional neural network (CNN), autoencoder, deep learning, and transformer. This paper also reviews pervasively used feature extractors and different types of input forms of convolutional neural network. At last, this review discusses challenges such as class imbalance and data leakage. It also discusses the trade-offs and suggestions about pre-processing techniques, deep learning, conventional machine learning methods, new techniques, and input type selection.

Indexed as

Alzheimer's diseaseclassificationconvolutional neural networkdeep learningmachine learningMagnetic Resonance Imagingneuroimagingtransformer

Identifiers

PMID36814932
PMCPMC9939698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.