Evidence map›Paper›PMID 36814913›Full record

ArticleFrontiers in immunology2023

Interleukin 17 B regulates colonic myeloid cell infiltration in a mouse model of DSS-induced colitis.

Xiaomin Zhang, Xiaokai Zhang, Xiaomei Song, Chuanying Xiang, Chunmei He, Yu Xie, Yangyang Zhou, Ning Wang, Gang Guo, Weijun Zhang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Xiaomin ZhangInstitute of Biopharmaceutical Research, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xiaokai ZhangNational Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.
Xiaomei SongDepartment of Gastroenterology, Chongqing General Hospital, Chongqing, China.
Chuanying XiangInstitute of Biopharmaceutical Research, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Chunmei HeDepartment of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing, China.
Yu XieInstitute of Biopharmaceutical Research, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yangyang ZhouInstitute of Biopharmaceutical Research, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Ning WangInstitute of Biopharmaceutical Research, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Gang GuoInstitute of Biopharmaceutical Research, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Weijun ZhangNational Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.
Yan LiInstitute of Biopharmaceutical Research, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Kaiyun LiuInstitute of Biopharmaceutical Research, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Quanming ZouNational Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.
Hong GuoDepartment of Gastroenterology, Chongqing General Hospital, Chongqing, China.
Yun ShiInstitute of Biopharmaceutical Research, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Army Medical University · CNSichuan University · CNWest China Hospital of Sichuan University · CNFirst People's Hospital of Chongqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytokines play vital roles in the pathogenesis of inflammatory bowel disease. IL17B is protective in the development of colitis. However, how IL17B regulates intestinal inflammation and what cells are regulated by IL17B is still unknown. Here, we aimed to illustrate the IL17B dependent cellular and molecular changes in colon tissue in a mouse colitis model. The results showed that IL17B expression in colon tissues was elevated in inflamed tissues than non-inflamed tissues of IBD patients. Wild type (WT) and

Indexed as

ColitisInterleukin-17AnimalsCytokinesImmunologic FactorsInflammationMiceMyeloid CellsCytokinesImmunologic FactorsInterleukin-17inflammatory bowel diseaseintestinal macrophagesmyeloid CellsneutrophilsS100A9single cell RNAseq

Identifiers

PMID36814913
PMCPMC9940313
OpenAlexW4319297119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.