Evidence map›Paper›PMID 36814695›Full record

ArticleJournal of mass spectrometry and advances in the clinical lab2023

Discovery of a biomarker for β-Thalassemia by HPLC-MS and improvement from Proton Transfer Reaction - Parallel Ion Parking.

Yuan Lin, Archana M Agarwal, Lissa C Anderson, Alan G Marshall

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of mass spectrometry and advances in the clinical lab, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Single-Frequency Ion Parking in a Digital 3D Quadrupole Ion Trap.International journal of mass spectrometry · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yuan LinDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32308, United States.
Archana M AgarwalDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84132, United States.
Lissa C AndersonIon Cyclotron Resonance Program, National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL 32310, United States.
Alan G MarshallDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32308, United States.
National High Magnetic Field Laboratory · USFlorida State University · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-thalassemia is a quantitative hemoglobin (Hb) disorder resulting in reduced production of Hb A and increased levels of Hb A

Indexed as

ACN, AcetonitrileAUC, Areas under the curveCID, Collision-induced dissociationESI, Electrospray ionizationETD, Electron-transfer dissociationFA, Formic acidFN, False-negativeFourier transform ion cyclotron resonanceFP, False-positiveFT-ICRFT-ICR, MS Fourier transform ion cyclotron resonance mass spectrometerFTMSHbA1d, Hb β with glutathioneHb A, Normal adult HbHb, HemoglobinIFCC, International Federation of Clinical Chemistry and Laboratory MedicineIQR, Interquartile rangeJ, Youden IndexMCW, Methanol/chloroform/waterMS, Mass spectrometrym/z, Mass-to-charge ratiosPTM, Post-translational modificationPTR-PIP, Proton transfer reaction-parallel ion parkingROC, Receiver operating characteristicSe(c), Sensitivity, the probability of a true positive)S/N, Signal-to-noise ratiosSp(c), Specificity, the probability of a true negative)TIC, Total ion chromatogramTN, True negativeTop-downTP, True positiveXIC, Extracted ion chromatogramsδ/β ratio

Identifiers

PMID36814695
PMCPMC9939715
OpenAlexW4318999660

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.