Postpyloric nutrition to prevent emergencies - a step away from repeat inpatient care in children with methylmalonic acidaemia and propionic acidaemia - a case report of four cases.

Stefan Schumann, Frank Risto Rommel, Serdar Cantez, Evdokia Alexanidou, Clemens Kamrath, Jan de Laffolie

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In one paragraph

Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Stefan SchumannDepartment of General Pediatrics and Neonatology, University of Giessen, Giessen, Germany.

Frank Risto RommelDepartment of General Pediatrics and Neonatology, University of Giessen, Giessen, Germany.

Serdar CantezDepartment of General Pediatrics and Neonatology, University of Giessen, Giessen, Germany.

Evdokia AlexanidouDepartment of General Pediatrics and Neonatology, University of Giessen, Giessen, Germany.

Clemens KamrathDepartment of General Pediatrics and Neonatology, University of Giessen, Giessen, Germany.

Jan de LaffolieDepartment of General Pediatrics and Neonatology, University of Giessen, Giessen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylmalonic acidaemia (MMA) and propionic acidaemia (PA) are very rare autosomal recessive inherited metabolic diseases from the group of organoacidopathies. Katabolism due to minor infections can lead to metabolic decompensation including hyperammonemia and ketoacidosis, especially in small children. We present data from a small cohort to clarify whether placement of a percutaneous endoscopic gastrostomy with jejunal tube (J-PEG) reduce metabolic imbalances and hospital stays. The aim is to prevent emergencies from occurring by preventing metabolic derailments at an early stage. 4 patients with MMA (

Indexed as

J-PEGmetabolic decompensationmethylmalonic acidaemiaMMAPApostpyloric nutritionprevention of emergenciespropionic acidaemia

Identifiers

PMID36814590

DOI10.3389/fped.2023.1078425

PMCPMC9939511

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.