Evidence map›Paper›PMID 36814585›Full record

ArticlePulmonary circulation2023

Right ventricular responses to CPAP therapy in obstructive sleep apnea: CMR analysis of the MOSAIC randomized trial.

Chinthaka B Samaranayake, Christopher Turnbull, Stefan Neubauer, Ilias Kylintireas, John Stradling, Sonya Craig, Colm McCabe

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chinthaka B SamaranayakeNational Pulmonary Hypertension Service Royal Brompton Hospital London UK.ORCID 0000-0003-3996-4205
Christopher TurnbullOxford Centre for Respiratory Medicine Oxford University Hospitals NHS Foundation Trust Oxford UK.
Stefan NeubauerNuffield Department of Experimental Medicine University of Oxford Oxford UK.
Ilias KylintireasNuffield Department of Experimental Medicine University of Oxford Oxford UK.
John StradlingNuffield Department of Experimental Medicine University of Oxford Oxford UK.
Sonya CraigOxford Centre for Respiratory Medicine Oxford University Hospitals NHS Foundation Trust Oxford UK.
Colm McCabeNational Pulmonary Hypertension Service Royal Brompton Hospital London UK.
Nuffield Orthopaedic Centre · GBRoyal Brompton Hospital · GBOxford University Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effects of continuous positive airway pressure (CPAP) on right ventricular (RV) function in patients with untreated mild-to-moderate obstructive sleep apnea (OSA) are unclear. In this exploratory analysis of cardiac magnetic resonance (CMR)-derived indices of RV function in patients with minimally symptomatic OSA from the MOSAIC randomized control trial we found no effect of CPAP on RV CMR parameters. In those with lower RV ejection fraction and higher RV end-diastolic volume (EDV) at baseline, CPAP treatment appeared to improve RV function with a significant reduction in both RV EDV and RV end-systolic volume although between-group effects were not observed. These data suggest potential merit in a larger randomized study of CPAP in patients with mild-to-moderate OSA and a greater breadth of RV dysfunction.

Indexed as

CPAPmagnetic resonance scanningmyocardial functionobstructive sleep apnearight ventricle

Identifiers

PMID36814585
PMCPMC9939623
OpenAlexW4319787735

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.