ArticleERJ open research2023
Unravelling young COPD and pre-COPD in the general population.
Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Incidence and Risk Factors for Progression from Pre-COPD to COPD: A Systematic Review and Meta‑analysis.International journal of chronic obstructive pulmonary disease · 2026Pooled it
- Normal spirometry with high and asthma-defining bronchodilator responsiveness: An appraisal from real-life data.Lung India : official organ of Indian Chest Society · 2026Article
- Aerosol deposition in the lung as a biomarker in asthma and chronic obstruction.Respiratory research · 2026Article
- Small Airway Disease in Pre-COPD and Early COPD: Insights Into the Pulmonary "Silent Zone".International journal of chronic obstructive pulmonary disease · 2026Review
- Evaluation of Clinical Characteristics and Lung Function Trajectories in Young COPD Patients Within the General Population.International journal of chronic obstructive pulmonary disease · 2026Article
- Effective determination of pre-chronic obstructive pulmonary disease by symptoms and CT features: a multicenter cross-sectional study.Journal of thoracic disease · 2025Article
- Research Progress of Sarcopenia Index in Chronic Obstructive Pulmonary Disease: A Review.Cureus · 2025Review
- Towards early detection and disease interception of COPD across the lifespan.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- The Prevalence of Emphysema in Patients Undergoing Lung Cancer Screening in a Middle-Income Country.Diseases (Basel, Switzerland) · 2025Article
- Role of impulse oscillometry in chronic obstructive pulmonary disease and asthma-chronic obstructive pulmonary disease overlap.Clinical and translational allergy · 2025Article
- Prevalence, diagnostic accuracy, and healthcare utilization patterns in patients with COPD in primary healthcare: a population-based study.NPJ primary care respiratory medicine · 2025Review
- Global, regional, and national burden of young COPD, 1990-2021, with forecasts to 2050: a systematic analysis for the global burden of disease study 2021.BMC public health · 2025Article
- Contrasting the clinical and biological characteristics of young and old COPD patients.ERJ open research · 2025Article
- Impacts of zinc enriched spirulina as an adjunct to conventional treatment of patients with Chronic Obstructive Pulmonary Disease: Study protocol for a North African randomized controlled trial (SPIRICOPD).La Tunisie medicale · 2024Article
- Postbronchodilator Spirometry Reference Values Are Needed and Helpful for Identifying Pre-Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2024Article
- An Italian Delphi Consensus on the Triple inhalation Therapy in Chronic Obstructive Pulmonary Disease.Multidisciplinary respiratory medicine · 2024Article
- COPD, PRISm and lung function reduction affect the brain cortical structure: a Mendelian randomization study.BMC pulmonary medicine · 2024Article
- Proportions and risk factors of chronic obstructive pulmonary disease and preserved ratio impaired spirometry, and association with small airway disease, in the positive screening older population from China: a cross-sectional study.BMC pulmonary medicine · 2024Article
- The many faces of COPD in real life: a longitudinal analysis of the NOVELTY cohort.ERJ open research · 2024Article
- Association between blood eosinophil count and small airway eosinophils in smokers with and without COPD.ERJ open research · 2023Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic obstructive pulmonary disease (COPD) is commonly diagnosed when the airflow limitation is well established and symptomatic. We aimed to identify individuals at risk of developing COPD according to the concept of pre-COPD and compare their clinical characteristics with 1) those who have developed the disease at a young age, and 2) the overall population with and without COPD. Methods: The EPISCAN II study is a cross-sectional, population-based study that aims to investigate the prevalence of COPD in Spain in subjects ≥40 years of age. Pre-COPD was defined as the presence of emphysema >5% and/or bronchial thickening by computed chromatography (CT) scan and/or diffusing capacity of the lung for carbon monoxide ( Results: Among the 1077 individuals with FEV Conclusions: 22.3% of the studied population was at risk of developing COPD, with similar symptomatic and structural changes to those with well-established disease without airflow obstruction. This COPD at-risk population is different from those that develop COPD at a young age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.