ArticleBMC psychology2023
Physical and cognitive function to explain the quality of life among older adults with cognitive impairment: exploring cognitive function as a mediator.
Article in BMC psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Effects of Carnosine on Cognitive Function and Mental Health-A Systematic Review and Meta-Analysis.Nutrients · 2026Pooled it
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- Effects of Nucleotide-RichNutrients · 2026Trial
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- A randomized, controlled trial to evaluate the efficacy of pyridoxine and ascorbic acid on cognitive function and quality of life in post-menopausal women.Naunyn-Schmiedeberg's archives of pharmacology · 2025Trial
- Trial
- Preliminary Effects of a Multicomponent Exercise Program Delivered in Conventional and Snoezelen Rooms Among Older Women Attending Social Centers: A Non-Randomized Pilot Study.Journal of functional morphology and kinesiology · 2026Article
- Effects of Fast Rhythmic Auditory Pacing on the Exercise Intensity of a Cognitive-Motor Training in Older Adults.European journal of sport science · 2026Article
- Assessing the dimensionality of the EQ-HWB-25 alongside EQ-5D-5L, QOL-ACC and ASCOT in an older adult population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- EEG-RCPNet: a cross-subject cognitive impairment detection model based on limited-channel eeg signals.Medical & biological engineering & computing · 2026Article
- Quality of life trajectories following geriatric hip fracture surgery: a growth mixture modelling approach.Journal of orthopaedic surgery and research · 2026Article
- Cognitive dysfunction, psychiatric distress, and functional decline after liver transplantation.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2025Article
- Functional status of Iranian older adults: a community-based assessment using EASY-care 2010.BMC geriatrics · 2025Article
- All-Cause Acute Illness Hospitalisations in the Preceding Two Years Are Associated With Cognitive Decline in Older Adults: The Sydney Memory and Ageing Study.International journal of geriatric psychiatry · 2025Article
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, 8-Week Pilot Study of Tuna-Byproduct-Derived Novel Supplements for Managing Cellular Senescence and Cognitive Decline in Perimenopausal and Postmenopausal Women.Antioxidants (Basel, Switzerland) · 2025Article
- Association between physical activity and cognitive function in a multi-ethnic Asian older adult population.Scientific reports · 2025Article
- Moderating effect of instrumental activities of daily living on the relationship between loneliness and depression in people with cognitive frailty.BMC geriatrics · 2025Article
- Impact of Pomegranate Extract Supplementation on Physical and Cognitive Function in Community-Dwelling Older Adults Aged 55-70 Years: A Randomised Double-Blind Clinical Trial.Geriatrics (Basel, Switzerland) · 2025Article
- The impact of physical activities on cognitive function among older adult populations: evidence from China.Frontiers in public health · 2025Article
- Sex differences in the association between cognitive function and 24-hour activity patterns in older adults: a compositional data analysis.Frontiers in aging · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
backgroundPhysical and cognitive function are both indicators of aging, characterized by a loss of adaptive response to life challenges and functional limitations, subsequently affecting their quality of life. This study aimed to identify the direct effect of physical function and the indirect effect of cognitive function on the quality of life in older adults with mild cognitive impairment.
methodsThe study participants were 79 older adults recruited from community centers in four urban districts of Korea. All participants completed a self-reported questionnaire for demographic characteristics and outcome variables. Outcome measures included physical function (grip strength, balance, and mobility), cognitive function, and mental and physical components of quality of life (QOL). Statistical analyses were conducted using hierarchical multiple linear regression and the PROCESS macro for mediation analysis.
resultsThe mean age of participants was 77.46 years old with an elementary or lower education level (53.2%). The mean score of cognitive function was 16.39 (SD = 6.5). Physical function (grip strength, balance, mobility) and cognitive function explained 25% of the variance in physical (p = 0.004) and 29% in mental (p < 0.001) components of QOL after controlling for age, sex, and education level. Mobility was associated with both physical (β=-0.27, p = 0.024) and mental (β=-0.36, p = 0.002) components of QOL. The cognitive function partially mediated the relationship between balance and the physical component of QOL; the proportion of mediation was 55%.
conclusionIn conclusion, physical and cognitive function were significant predictors of QOL in older adults with cognitive impairment. Specifically, balance has significant indirect effects on the physical component of QOL through cognitive function as a mediator. Health-promoting strategies could be more effective when focusing on the direct effect of physical function as well as the mediating effect of cognitive function to promote the quality of life in this population.
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