Evidence map›Paper›PMID 36814220›Full record

ArticleThe journal of headache and pain2023

Alterations in regional homogeneity and multiple frequency amplitudes of low-frequency fluctuation in patients with new daily persistent headache: a resting-state functional magnetic resonance imaging study.

Xueyan Zhang, Wei Wang, Xiaoyan Bai, Yanliang Mei, Hefei Tang, Ziyu Yuan, Xue Zhang, Zhiye Li, Peng Zhang, Zhangxuan Hu and 4 more

Open access · goldAbstract read
In one paragraph

Article in The journal of headache and pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

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  10. Sex differences in anhedonia in bipolar depression: a resting-state fMRI study.European archives of psychiatry and clinical neuroscience · 2025
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  18. XCP-D: A robust pipeline for the post-processing of fMRI data.Imaging neuroscience (Cambridge, Mass.) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Xueyan Zhang *Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China.ORCID http://orcid.org/0000-0002-9898-6423
Wei Wang *Headache Center, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0003-2302-6273
Xiaoyan BaiTiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, Beijing, China.
Yanliang MeiHeadache Center, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hefei TangHeadache Center, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ziyu YuanHeadache Center, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xue ZhangTiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, Beijing, China.
Zhiye LiTiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, Beijing, China.
Peng ZhangHeadache Center, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhangxuan HuGE Healthcare, Beijing, China.
Yaqing ZhangHeadache Center, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xueying YuHeadache Center, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Binbin SuiTiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, Beijing, China. reneesui@163.com.
Yonggang WangHeadache Center, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. w100yg@gmail.com.
Capital Medical University · CNNational Clinical Research Center for Digestive Diseases · CN

Funding

National Natural Science Foundation of Beijing Z200024National Natural Science Foundation of China 32170752
6 · The paper itself

Abstract

backgroundNew daily persistent headache (NPDH) is a rare primary headache that is highly disabling. The pathophysiology of NDPH is still unclear, and we aimed to reveal the underlying mechanism of NDPH through functional magnetic resonance imaging (fMRI) analysis.

methodsIn this cross-sectional study, thirty patients with NDPH and 30 healthy controls (HCs) were recruited. The blood oxygen level-dependent (BOLD) sequences of all participants were obtained using the GE 3.0 T system. We performed ReHo, ALFF (conventional band: 0.01-0.08 Hz, slow-5: 0.01-0.027 Hz, slow-4: 0.027-0.073 Hz) and seed-based to the whole brain functional connectivity (FC) analysis in the NDPH and HC groups. The sex difference analysis of ReHo, ALFF, and FC values was conducted in the NDPH group. We also conducted Pearson's correlation analysis between ReHo, ALFF, FC values and clinical characteristics (pain intensity, disease duration, HIT-6, GAD-7, PHQ-9, and PSQI scores).

resultsBoth increased ReHo (P

conclusionsPatients with NDPH may have abnormal activation of the visual system. Abnormal visual activation may occur mainly in higher frequency band of the classical band. No sex differences in brain activity were found in patients with NDPH.

Indexed as

Brain MappingHeadache DisordersBrainCross-Sectional StudiesHeadacheHumansMagnetic Resonance ImagingAmplitude of low-frequency fluctuationFunctional connectivityMultiple frequenciesNew daily persistent headacheRegional homogeneity

Identifiers

PMID36814220
PMCPMC9946707
OpenAlexW4321487381

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.