Evidence map›Paper›PMID 36813996›Full record

ArticleEye (London, England)2023

Non-invasive endothelial cell density measurement of in toto pre-stripped DMEK-roll - impact of pre- and intraoperative endothelial cell loss on postoperative midterm clinical outcome.

Kolja Berg, Tarek Safi, Berthold Seitz, Loay Daas

Abstract readComment
In one paragraph

Article in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Kolja BergDepartment of Ophthalmology, Saarland University Medical Center, Homburg, Germany. kobe@mailbox.org.ORCID 0000-0002-4038-0955
Tarek SafiDepartment of Ophthalmology, Saarland University Medical Center, Homburg, Germany.
Berthold SeitzDepartment of Ophthalmology, Saarland University Medical Center, Homburg, Germany.ORCID 0000-0001-9701-8204
Loay DaasDepartment of Ophthalmology, Saarland University Medical Center, Homburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTo measure the endothelial cell density (ECD) of the in toto pre-stripped endothelial Descemet membrane lamellae (EDML) and to describe the impact of pre- and intraoperative endothelial cell loss (ECL) on postoperative midterm clinical outcome. SUBJECTS/

methodsThe ECD of 56 Corneoscleral Donor Discs (CDD) was first measured with an inverted specular microscope (t0

resultsThe average ECD (in cells/mm²) at time points t0

conclusionOur results indicate that the non-invasive ECD measurement of the prestripped EDML roll before its transplantation is feasible. Despite significantly decreasing ECD up to 6 months postoperatively, visual acuity further improved and thickness further decreased up to 1 year postoperatively.

Indexed as

Descemet Stripping Endothelial KeratoplastyFuchs' Endothelial DystrophyCell CountEndothelial CellsEndothelium, CornealHumansRetrospective Studies

Identifiers

PMID36813996
PMCPMC10516950

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.