Evidence map›Paper›PMID 36813950›Full record

ArticleVirchows Archiv : an international journal of pathology2023

Prognostic significance and immune correlates of FADD in penile squamous cell carcinoma.

Ting Xue, Ru Yan, Zaishang Li, Shengjie Guo, Xiao Xiao, Jietian Jin, Lijuan Jiang, Huali Ma, Chong Wu, Tingyu Liu and 6 more

Abstract read
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In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Ting Xue *Department of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China.
Ru Yan *Department of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China.
Zaishang LiDepartment of Urology, Shenzhen People's Hospital, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, 518060, China.
Shengjie GuoDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China.
Xiao XiaoDepartment of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Jietian JinDepartment of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Lijuan JiangDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China.
Huali MaDepartment of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Chong WuDepartment of General Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Tingyu LiuDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China.
Lichao WeiDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China.
Longbin XiongDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China.
Fangjian ZhouDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China.
Kai YaoDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China.
Ranyi LiuDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China. liury@sysucc.org.cn.
Hui HanDepartment of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, 510060, China. hanhui@sysucc.org.cn.
Sun Yat-sen University · CNSun Yat-sen University Cancer Center · CNState Key Laboratory of Oncology in South ChinaSouthern University of Science and Technology · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

National Natural Science Foundation of China-China Academy of General Technology Joint Fund for Basic Research 81772755
6 · The paper itself

Abstract

Penile squamous cell carcinoma (PSCC) with a poor prognosis lacks reliable biomarkers for stratifying patients. Fas-associated death domain (FADD) could regulate cell proliferation and has shown promising diagnostic and prognostic significance in multiple cancers. However, researchers have not determined how FADD exerts its effect on PSCC. In this study, we set out to investigate the clinical features of FADD and the prognostic impact of PSCC. Additionally, we also assessed the role of affecting the immune environment in PSCC. Immunohistochemistry was carried out to evaluate the protein expression of FADD. The difference between FADD

Indexed as

Carcinoma, Squamous CellPenile NeoplasmsB7-H1 AntigenBiomarkersBiomarkers, TumorFas-Associated Death Domain ProteinForkhead Transcription FactorsHumansMalePrognosisB7-H1 AntigenBiomarkersBiomarkers, TumorFADD protein, humanFas-Associated Death Domain ProteinForkhead Transcription FactorsBiomarkerChemotherapyFADDPenile squamous cell carcinomaTumor microenvironment

Identifiers

PMID36813950
OpenAlexW4321487472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.