Evidence map›Paper›PMID 36813902›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2023

Maternal hypertensive disorders and survival without major morbidities among extremely low gestation newborns.

Martha B Kole-White, Shampa Saha, Erika F Werner, Sanjay Chawla, Martin Keszler, Elisabeth C McGowan, Myra H Wyckoff, Abbot R Laptook, Generic Database Subcommittee of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network

Registry-linked trialOpen access · greenAbstract readClinical Trial
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00063063 (Generic Database), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00063063 recruitingnot on this map

Generic Database: A Survey of Morbidity and Mortality in Very Low Birth Weight Infants

TypeobservationalSponsorNICHD Neonatal Research NetworkRan1987 to 2030Enrolled80,000ConditionsInfant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, PrematureArmsNo Intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Martha B Kole-WhiteDivision of Maternal Fetal Medicine, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, RI, US. mkolewhite@kentri.org.ORCID 0000-0003-1378-3254
Shampa SahaSocial, Statistical and Environmental Sciences Unit, RTI International, Research Triangle Park, Durham, NC, US.ORCID 0000-0002-8305-3495
Erika F WernerDepartment of Obstetrics and Gynecology, Tufts University School of Medicine, Boston, MA, US.
Sanjay ChawlaDepartment of Pediatrics, Central Michigan University, Wayne State University, Detroit, MI, US.ORCID 0000-0002-7299-2737
Martin KeszlerDepartment of Pediatrics, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, RI, US.ORCID 0000-0002-9964-664X
Elisabeth C McGowanDepartment of Pediatrics, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, RI, US.
Myra H WyckoffDepartment of Pediatrics, UT Southwestern Medical Center at Dallas, Dallas, TX, US.
Abbot R LaptookDepartment of Pediatrics, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, RI, US.ORCID 0000-0001-9848-3466
Generic Database Subcommittee of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Brown University · USSouthwestern Medical CenterCentral Michigan University · USRTI International · USTufts University · US

Funding

NICHD Cooperative Multicenter Neonatal Research NetworkU10HD040689 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI WYCKOFF, MYRA HELEN · 2001 to 2015
$5.6M
NICHD Neonatal Research Network -- Cincinnati Clinical CenterUG1HD027853 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI STEPHANIE L MERHAR · 2016 to 2026
$3.7M
NICHD COPPERATIVE MULTICENTER NEONATAL RESEARCH NETWORKUG1HD040689 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI Myra Helen Wyckoff · 2016 to 2026
$3.5M
NICHD Neonatal Research Network - Stanford UniversityUG1HD027880 · NICHD · STANFORD UNIVERSITY · PI Valerie Chock · 2016 to 2026
$3.3M
Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal ResearchNetworkUG1HD053089 · NICHD · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Janell Fuller, Jessie R. Maxwell · 2016 to 2026
$3.2M
NICHD Neonatal Research NetworkUG1HD027904 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI MARON, JILL LAMANNA · 2016 to 2024
$2.1M
NICHD Neonatal Research Network (NRN): Clinical Centers (UG1 Clinical Trial OptionalUG1HD112093 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Matthew Albert Rysavy · 2023 to 2026
$1.4M
NICHD NIH HHS UG1 HD027853NICHD NIH HHS UG1 HD027880NICHD NIH HHS UG1 HD027904NICHD NIH HHS UG1 HD040689NICHD NIH HHS UG1 HD053089
6 · The paper itself

Abstract

objectiveEvaluate if odds of survival without major morbidity are higher among extremely low gestation neonates (ELGANs) born to mothers with chronic hypertension (cHTN) or hypertensive disorders of pregnancy (HDP) compared to ELGANs born to mothers without hypertension (HTN). STUDY

designRetrospective study of prospectively collected data from the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Included children had a birthweight of 401-1000 g and/or gestational age of 22

resultsSurvival without morbidities for newborns of mothers with no HTN, cHTN and HDP (29.1%, 32.9%, 37.0% respectively) did not differ after adjustment.

conclusionAfter adjusting for contributing variables maternal HTN is not associated with improved survival free of morbidity among ELGANs. TRIALS REGISTRATION: clinicaltrials.gov Identifier: NCT00063063 (generic database).

Indexed as

Hypertension, Pregnancy-InducedPre-EclampsiaBirth WeightChildFemaleHumansInfantInfant, NewbornMorbidityPregnancyRetrospective Studies

Identifiers

PMID36813902
PMCPMC10107366
OpenAlexW4321483016

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.