Evidence map›Paper›PMID 36813901›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2023

A sepsis trigger tool reduces time to antibiotic administration in the NICU.

Avery Forget, Comfort Adegboye, Maria Alfieri, Ramy Yim, Kathleen Flaherty, Himi Mathur, Amy E O'Connell

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Avery ForgetDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA.
Comfort AdegboyeDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA.
Maria AlfieriDepartment of Pediatrics Quality Program, Boston Children's Hospital, Boston, MA, USA.
Ramy YimDepartment of Pediatrics Quality Program, Boston Children's Hospital, Boston, MA, USA.
Kathleen FlahertyInfection Prevention, Boston Children's Hospital, Boston, MA, USA.
Himi MathurDepartment of Pediatrics Quality Program, Boston Children's Hospital, Boston, MA, USA.
Amy E O'ConnellDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA. amy.oconnell@childrens.harvard.edu.ORCID 0000-0002-9298-6991

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveProlonged time to antibiotic administration is associated with increased morbidity and mortality. Interventions to decrease the time to antibiotic administration may improve mortality and morbidity. STUDY

designWe identified possible change concepts for reducing time to antibiotic usage in the NICU. For the initial intervention, we developed a sepsis screening tool based on NICU-specific parameters. The main goal of the project was to reduce time to antibiotic administration by 10%.

resultsThe project was conducted from April 2017 until April 2019. There were no missed cases of sepsis in the project period. Time to antibiotic administration for patients who were started on antibiotics decreased during the project, with the mean shifting from 126 to 102 min, a reduction of 19%.

conclusionsWe successfully reduced time to antibiotic delivery in our NICU using a trigger tool to identifying potential cases of sepsis in the NICU environment. The trigger tool requires broader validation.

Indexed as

Intensive Care Units, NeonatalSepsisAnti-Bacterial AgentsHumansInfant, NewbornAnti-Bacterial Agents

Identifiers

PMID36813901

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.