Evidence map›Paper›PMID 36813833›Full record

ArticleScientific reports2023

Acquired radioresistance in EMT6 mouse mammary carcinoma cell line is mediated by CTLA-4 and PD-1 through JAK/STAT/PI3K pathway.

Nur Fatihah Ronny Sham, Narimah Abdul Hamid Hasani, Nurhaslina Hasan, Muhammad Khalis Abdul Karim, Syed Baharom Syed Ahmad Fuad, Harissa Husainy Hasbullah, Mohammad Johari Ibahim

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nur Fatihah Ronny ShamFaculty of Medicine, Jalan Hospital, Universiti Teknologi MARA, Selangor Branch, Sungai Buloh Campus, 47000, Sungai Buloh, Selangor, Malaysia.
Narimah Abdul Hamid HasaniFaculty of Medicine, Jalan Hospital, Universiti Teknologi MARA, Selangor Branch, Sungai Buloh Campus, 47000, Sungai Buloh, Selangor, Malaysia.
Nurhaslina HasanFaculty of Dentistry, Jalan Hospital, Universiti Teknologi MARA, Selangor Branch, Sungai Buloh Campus, 47000, Sungai Buloh, Selangor, Malaysia.
Muhammad Khalis Abdul KarimFaculty of Science, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Syed Baharom Syed Ahmad FuadFaculty of Medicine, Jalan Hospital, Universiti Teknologi MARA, Selangor Branch, Sungai Buloh Campus, 47000, Sungai Buloh, Selangor, Malaysia.
Harissa Husainy HasbullahFaculty of Medicine, Jalan Hospital, Universiti Teknologi MARA, Selangor Branch, Sungai Buloh Campus, 47000, Sungai Buloh, Selangor, Malaysia.
Mohammad Johari IbahimFaculty of Medicine, Jalan Hospital, Universiti Teknologi MARA, Selangor Branch, Sungai Buloh Campus, 47000, Sungai Buloh, Selangor, Malaysia. mji@uitm.edu.my.
Hospital Sungai Buloh · MYUniversiti Putra Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer recurrence is often associated with the acquisition of radioresistance by cancer tissues due to failure in radiotherapy. The underlying mechanism leading to the development of acquired radioresistance in the EMT6 mouse mammary carcinoma cell line and the potential pathway involved was investigated by comparing differential gene expressions between parental and acquired radioresistance cells. EMT6 cell line was exposed to 2 Gy/per cycle of gamma-ray and the survival fraction between EMT6-treated and parental cells was compared. EMT6

Indexed as

Breast NeoplasmsCTLA-4 AntigenPhosphatidylinositol 3-KinasesProgrammed Cell Death 1 ReceptorRadiation ToleranceAnimalsCell Line, TumorMiceCTLA-4 AntigenPhosphatidylinositol 3-KinasesProgrammed Cell Death 1 Receptor

Identifiers

PMID36813833
PMCPMC9946948
OpenAlexW4321480306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.