ReviewTranslational psychiatry2023
Seasonality of brain function: role in psychiatric disorders.
Review in Translational psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 75 citations in OpenAlex.
- Defining Clock Neurons Within Distributed Circadian Circuits Through Multiscale Technologies.Journal of biological rhythms · 2026Review
- Neuropsychiatric outcomes after montelukast versus inhaled corticosteroids in pediatric asthma: a pooled birth cohort study.BMC medicine · 2026Article
- Primary Care Prescribing Patterns for Benzodiazepines and Z-Drugs, and Evidence Gaps Concerning Hydroxyzine and Seasonality: A Systematic Review.Clinics and practice · 2026Review
- Splicing of a core circadian clock gene regulates seasonal adaptations by a winter gating mechanism.Science advances · 2026Article
- Not just spontaneous remission: Time-dependent and independent effects in pre-intervention symptom reduction.Internet interventions · 2026Article
- Seasonal surge for mental health demand in the emergency department of Eradah complex for mental health in the Eastern Province of Saudi Arabia: a retrospective study.The Journal of the Egyptian Public Health Association · 2026Article
- Dense longitudinal neuroimaging reveals individual brain change trajectories.Trends in cognitive sciences · 2026Review
- A Comparative Analysis of Psychiatric Consultations Across Emergency, Hospital, and Community Mental Health Settings.Journal of clinical medicine · 2026Article
- Bright Light Therapy in Psychiatric Disorders: Mechanisms, Clinical Procedures and Evidence.Life (Basel, Switzerland) · 2026Review
- Body, mind, and weather: mechanisms of interaction - a narrative review.Postepy psychiatrii neurologii · 2026Review
- Research priorities for mental health and circadian science: a priority setting partnership of individuals with lived experience, carers, clinicians and researchers.BMJ mental health · 2026Article
- Association between differences in ambient light exposure by hospital bed location and depressive symptoms among postpartum women.Frontiers in psychiatry · 2026Article
- Factors associated with psychiatric admission from observation beds in the psychiatric emergency room.Frontiers in psychiatry · 2026Article
- Effects of dance training on oxytocin secretion and neural activity in older adults with subjective cognitive decline.Innovation in aging · 2026Article
- Shorter sleep, higher odds: a nationally representative analysis of the dose-dependent link to depression among 48.8 million U.S. youth.Frontiers in pediatrics · 2026Article
- Regional activity within the human amygdala varies with season, mood and illuminance.Nature communications · 2025Article
- Effects of seasonal factors on brain function: Systematic review and future perspectives.iScience · 2025Article
- Splicing of a core clock gene regulates seasonal adaptations by a winter gating mechanism.bioRxiv : the preprint server for biology · 2025Article
- Changes in Rest-Activity Rhythms in Adolescents as They Age: Associations With Brain and Behavioral Changes in the ABCD Study.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Article
- Rates of Suicide Ideation and Associated Risk Factors Among Female Secondary School Students in Iraq.Healthcare (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Seasonality patterns are reported in various psychiatric disorders. The current paper summarizes findings on brain adaptations associated with seasonal changes, factors that contribute to individual differences and their implications for psychiatric disorders. Changes in circadian rhythms are likely to prominently mediate these seasonal effects since light strongly entrains the internal clock modifying brain function. Inability of circadian rhythms to accommodate to seasonal changes might increase the risk for mood and behavior problems as well as worse clinical outcomes in psychiatric disorders. Understanding the mechanisms that account for inter-individual variations in seasonality is relevant to the development of individualized prevention and treatment for psychiatric disorders. Despite promising findings, seasonal effects are still understudied and only controlled as a covariate in most brain research. Rigorous neuroimaging studies with thoughtful experimental designs, powered sample sizes and high temporal resolution alongside deep characterization of the environment are needed to better understand the seasonal adaptions of the human brain as a function of age, sex, and geographic latitude and to investigate the mechanisms underlying the alterations in seasonal adaptation in psychiatric disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.