Evidence map›Paper›PMID 36813487›Full record

ArticleBMJ open2023

Knowledge, attitudes and practices regarding antimicrobial use and resistance among healthcare seekers in two tertiary hospitals in Ghana: a quasi-experimental study.

Evans Otieku, Ama Pokuaa Fenny, Appiah-Koran Labi, Alex Kwame Owusu-Ofori, Jørgen Kurtzhals, Ulrika Enemark

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Evans OtiekuEconomics Division, Institute of Statistical, Social, and Economic Research (ISSER), University of Ghana, Legon, Ghana otieku@yahoo.com.ORCID 0000-0002-6809-5160
Ama Pokuaa FennyEconomics Division, Institute of Statistical, Social, and Economic Research (ISSER), University of Ghana, Legon, Ghana.ORCID 0000-0001-9367-1265
Appiah-Koran LabiDepartment of Medical Microbiology, University of Ghana Medical School, Accra, Ghana.
Alex Kwame Owusu-OforiLaboratory Services Directorate, Komfo Anokye Teaching Hospital, Kumasi, Ghana.ORCID 0000-0002-2172-8645
Jørgen KurtzhalsISIM, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-2760-8713
Ulrika EnemarkDepartment of Public Health, Aarhus University, Aarhus, Denmark.
University of Ghana · GHAarhus University · DKKomfo Anokye Teaching Hospital · GHUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate knowledge of antimicrobial resistance (AMR), to study how the judgement of health value (HVJ) and economic value (EVJ) affects antibiotic use, and to understand if access to information on AMR implications may influence perceived AMR mitigation strategies.

designA quasi-experimental study with interviews performed before and after an intervention where hospital staff collected data and provided one group of participants with information about the health and economic implications of antibiotic use and resistance compared with a control group not receiving the intervention.

settingKorle-Bu and Komfo Anokye Teaching Hospitals, Ghana.

participantsAdult patients aged 18 years and older seeking outpatient care.

main outcome measuresWe measured three outcomes: (1) level of knowledge of the health and economic implications of AMR; (2) HVJ and EVJ behaviours influencing antibiotic use and (3) differences in perceived AMR mitigation strategy between participants exposed and not exposed to the intervention.

resultsMost participants had a general knowledge of the health and economic implications of antibiotic use and AMR. Nonetheless, a sizeable proportion disagreed or disagreed to some extent that AMR may lead to reduced productivity/indirect costs (71% (95% CI 66% to 76%)), increased provider costs (87% (95% CI 84% to 91%)) and costs for carers of AMR patients/societal costs (59% (95% CI 53% to 64%)). Both HVJ-driven and EVJ-driven behaviours influenced antibiotic use, but the latter was a better predictor (reliability coefficient >0.87). Compared with the unexposed group, participants exposed to the intervention were more likely to recommend restrictive access to antibiotics (p<0.01) and pay slightly more for a health treatment strategy to reduce their risk of AMR (p<0.01).

conclusionThere is a knowledge gap about antibiotic use and the implications of AMR. Access to AMR information at the point of care could be a successful way to mitigate the prevalence and implications of AMR.

Indexed as

Anti-Bacterial AgentsHealth Knowledge, Attitudes, PracticeAdultGhanaHumansReproducibility of ResultsSurveys and QuestionnairesTertiary Care CentersAnti-Bacterial Agentshealth policyhealth & safetypublic health

Identifiers

PMID36813487
PMCPMC9950892
OpenAlexW4321503789

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.