Evidence map›Paper›PMID 36813081›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2023

Clinical characteristics and outcomes of hospital-manifested COVID-19 among Brazilians.

Polianna Delfino-Pereira, Magda Carvalho Pires, Virginia Mara Reis Gomes, Matheus Carvalho Alves Nogueira, Maria Clara Pontello Barbosa Lima, Alexandre Vargas Schwarzbold, Amanda de Oliveira Maurílio, Ana Luiza Bahia Alves Scotton, André Soares de Moura Costa, Barbara Lopes Farace and 42 more

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Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

52 authors.

Polianna Delfino-PereiraUniversidade Federal de Minas Gerais, Belo Horizonte, Brazil; Institute for Health Technology Assessment (IATS/ CNPq), Porto Alegre, Brazil. Electronic address: polidelfino@yahoo.com.br.
Magda Carvalho PiresUniversidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address: magdacpires@gmail.com.
Virginia Mara Reis GomesUniversidade Federal de Minas Gerais, Belo Horizonte, Brazil; Centro Universitário de Belo Horizonte (UniBH), Belo Horizonte, Brazil. Electronic address: vgvirginiagomes@gmail.com.
Matheus Carvalho Alves NogueiraHospitais da Rede Mater Dei, Belo Horizonte, Brazil. Electronic address: mathnogueira42@gmail.com.
Maria Clara Pontello Barbosa LimaUniversidade Federal de Ouro Preto, Ouro Preto, Brazil. Electronic address: mariaclarapontellobl@gmail.com.
Alexandre Vargas SchwarzboldUniversidade Federal de Santa Maria/Hospital Universitário/EBSERH, Santa Maria, Brazil. Electronic address: alexvspoa@gmail.com.
Amanda de Oliveira MaurílioHospital São João de Deus, São João de Deus, Brazil. Electronic address: amandaoliveira.maurilio@gmail.com.
Ana Luiza Bahia Alves ScottonHospital Regional Antônio Dias, Patos de Minas, Brazil. Electronic address: analuiza.bahia@yahoo.com.br.
André Soares de Moura CostaHospitais da Rede Mater Dei, Belo Horizonte, Brazil. Electronic address: andresmc@gmail.com.
Barbara Lopes FaraceHospital Risoleta Tolentino Neves, Belo Horizonte, Brazil. Electronic address: barbarafarace@gmail.com.
Bruno Mateus de CastroHospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. Electronic address: brunocastro1199@gmail.com.
Christiane Corrêa Rodrigues CiminiHospital Santa Rosália. R, Teófilo Otoni, Brazil; Mucuri Medical School (FAMMUC), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Teófilo Otoni, Brazil. Electronic address: christiane.cimini@gmail.com.
Daniel Vitório SilveiraHospital Unimed BH, Belo Horizonte, Brazil. Electronic address: danielvez@gmail.com.
Daniela PonceFaculdade de Medicina de Botucatu - Universidade Estadual Paulista "Júlio de Mesquita Filho". Av. Prof. Mário Rubens Guimarães Montenegro, s/n - UNESP - Campus de Botucatu, Botucatu, Brazil. Electronic address: daniela.ponce@unesp.br.
Elayne Crestani PereiraHospital SOS Cárdio, Florianópolis, Brazil. Electronic address: elaynepp@yahoo.com.br.
Eliane Würdig RoeschHospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. Electronic address: eroesch@hcpa.edu.br.
Euler Roberto Fernandes ManentiHospital Mãe de Deus, Porto Alegre, Brazil. Electronic address: eulermanenti@gmail.com.
Evelin Paola de Almeida CenciHospital Universitário Canoas, Canoas, Brazil. Electronic address: assistencial6_hu@centrodepesquisaclinica.com.br.
Fernanda Costa Dos SantosHospital Nossa Senhora da Conceição and Hospital Cristo Redentor, Porto Alegre, Brazil. Electronic address: fcdsantos86@gmail.com.
Fernando AnschauHospital Nossa Senhora da Conceição and Hospital Cristo Redentor, Porto Alegre, Brazil. Electronic address: afernando@ghc.com.br.
Fernando Graça AranhaHospital SOS Cárdio, Florianópolis, Brazil. Electronic address: fgaranha@icloud.com.
Frederico BartolazziHospital Santo Antônio. Praça Dr. Márcio Carvalho Lopes Filho, Curvelo, Brazil. Electronic address: fredlazzi@hotmail.com.
Guilherme Fagundes NascimentoHospital Unimed BH, Belo Horizonte, Brazil. Electronic address: guilhermefagundesn@hotmail.com.
Heloisa Reniers ViannaHospital Universitário Ciências Médicas, Belo Horizonte, Brazil. Electronic address: hrvianna@hotmail.com.
Joanna d'Arc Lyra BatistaInstitute for Health Technology Assessment (IATS/ CNPq), Porto Alegre, Brazil; Universidade Federal da Fronteira Sul, Chapecó, Brazil; Hospital Regional do Oeste. R. Florianópolis, Chapecó, Brazil. Electronic address: joannalyra@gmail.com.
Joice Coutinho de AlvarengaFundação Hospitalar do Estado de Minas Gerais (FHEMIG). Cidade Administrativa de Minas Gerais, Belo Horizonte, Brazil. Electronic address: joice-alvarenga@hotmail.com.
Juliana da Silva Nogueira CarvalhoHospital das Clínicas da Universidade Federal de Pernambuco, Recife, Brazil. Electronic address: juliana.nogueira@ufpe.br.
Juliana Machado-RugoloFaculdade de Medicina de Botucatu - Universidade Estadual Paulista "Júlio de Mesquita Filho". Av. Prof. Mário Rubens Guimarães Montenegro, s/n - UNESP - Campus de Botucatu, Botucatu, Brazil. Electronic address: jr.machado@unesp.br.
Karen Brasil RuschelHospital Mãe de Deus, Porto Alegre, Brazil; Hospital Universitário Canoas, Canoas, Brazil. Electronic address: karenbruschel@gmail.com.
Luanna Silva Monteiro MenezesHospital Luxemburgo, Belo Horizonte, Brazil; Hospital Metropolitano Odilon Behrens, Belo Horizonte, Brazil. Electronic address: luannasmonteiro@gmail.com.
Luís César de CastroHospital Bruno Born, Lajeado, Brazil. Electronic address: pharmlucamsc@gmail.com.
Luiz Antônio NasiHospital Moinhos de Vento, Porto Alegre, Brazil. Electronic address: lnasi@terra.com.br.
Maiara Anschau FlorianiHospital Moinhos de Vento, Porto Alegre, Brazil. Electronic address: mai.anschau@gmail.com.
Maíra Dias SouzaHospital Metropolitano Odilon Behrens, Belo Horizonte, Brazil. Electronic address: mairadiassouza@gmail.com.
Maíra Viana Rego Souza-SilvaUniversidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address: mairavsouza@gmail.com.
Marcelo CarneiroHospital Santa Cruz, Santa Cruz do Sul, Brazil. Electronic address: marceloc@unisc.br.
Maria Aparecida Camargos BicalhoUniversidade Federal de Minas Gerais, Belo Horizonte, Brazil; Fundação Hospitalar do Estado de Minas Gerais (FHEMIG). Cidade Administrativa de Minas Gerais, Belo Horizonte, Brazil. Electronic address: macbicalho@gmail.com.
Mariana Frizzo de GodoyHospital São Lucas PUCRS, Av. Ipiranga, 6690, Porto Alegre, Brazil. Electronic address: mfdegodoy@gmail.com.
Milton Henriques Guimarães-JúniorHospital Márcio Cunha, Ipatinga, Brazil. Electronic address: miltonhenriques@yahoo.com.br.
Patricia Klarmann ZiegelmannInstitute for Health Technology Assessment (IATS/ CNPq), Porto Alegre, Brazil; Hospital Tacchini. R, Bento Gonçalves, Brazil. Electronic address: patriciakz99@gmail.com.
Pedro Ledic AssafHospital Metropolitano Doutor Célio de Castro, Belo Horizonte, Brazil. Electronic address: pedro.ledic@hmdcc.com.br.
Petrônio José de Lima MartelliHospital das Clínicas da Universidade Federal de Pernambuco, Recife, Brazil. Electronic address: petroniocarla@uol.com.br.
Renan Goulart FingerHospital Regional do Oeste. R. Florianópolis, Chapecó, Brazil. Electronic address: renanfinger@yahoo.com.br.
Saionara Cristina FranciscoHospital Metropolitano Doutor Célio de Castro, Belo Horizonte, Brazil. Electronic address: saionaracf@gmail.com.
Silvia Ferreira AraújoHospital Semper, Belo Horizonte, Brazil. Electronic address: silviaferreiragastro@gmail.com.
Talita Fischer OliveiraHospital Metropolitano Odilon Behrens, Belo Horizonte, Brazil. Electronic address: talitafischeroliveira@gmail.com.
Thainara Conceição de OliveiraHospital Universitário Canoas, Canoas, Brazil. Electronic address: thainarastaehler@hotmail.com.
Thalita Martins LageHospital Márcio Cunha, Ipatinga, Brazil. Electronic address: thalitalage@hotmail.com.
Vanessa MullerHospital São Lucas PUCRS, Av. Ipiranga, 6690, Porto Alegre, Brazil. Electronic address: muller.co.vanessa@gmail.com.
Yuri Carlotto RamiresHospital Bruno Born, Lajeado, Brazil. Electronic address: yuri.ramires@gmail.com.
Teresa Cristina de Abreu FerrariUniversidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address: tferrari@medicina.ufmg.br.
Milena Soriano MarcolinoUniversidade Federal de Minas Gerais, Belo Horizonte, Brazil; Institute for Health Technology Assessment (IATS/ CNPq), Porto Alegre, Brazil; Telehealth Center, University Hospital, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address: milenamarc@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo analyze the clinical characteristics and outcomes of admitted patients with the hospital- versus community-manifested COVID-19 and to evaluate the risk factors related to mortality in the first population.

methodsThis retrospective cohort included consecutive adult patients with COVID-19, hospitalized between March and September 2020. The demographic data, clinical characteristics, and outcomes were extracted from medical records. Patients with hospital-manifested COVID-19 (study group) and those with community-manifested COVID-19 (control group) were matched by the propensity score model. Logistic regression models were used to verify the risk factors for mortality in the study group.

resultsAmong 7,710 hospitalized patients who had COVID-19, 7.2% developed symptoms while admitted for other reasons. Patients with hospital-manifested COVID-19 had a higher prevalence of cancer (19.2% vs 10.8%) and alcoholism (8.8% vs 2.8%) than patients with community-manifested COVID-19 and also had a higher rate of intensive care unit requirement (45.1% vs 35.2%), sepsis (23.8% vs 14.5%), and death (35.8% vs 22.5%) (P <0.05 for all). The factors independently associated with increased mortality in the study group were increasing age, male sex, number of comorbidities, and cancer.

conclusionHospital-manifested COVID-19 was associated with increased mortality. Increasing age, male sex, number of comorbidities, and cancer were independent predictors of mortality among those with hospital-manifested COVID-19 disease.

Indexed as

COVID-19AdultComorbidityHospitalizationHospital MortalityHospitalsHumansMaleRetrospective StudiesRisk FactorsSARS-CoV-2South American PeopleClinical characteristicsCOVID-19Hospital-manifested infectionIn-hospital mortalityOutcomesRisk factors

Identifiers

PMID36813081
PMCPMC9941311

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