ArticleEnvironmental research2023
The association of prenatal phthalates, organophosphorous pesticides, and organophosphate esters with early child language ability in Norway.
Article in Environmental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Prenatal exposure to organophosphate esters and child cognitive development in the MARBLES prospective cohort.International journal of hygiene and environmental health · 2026Article
- Article
- Associations of Exposure to Common Plasticizers and Organophosphate Pesticides during Pregnancy and in Childhood with Cognitive Performance in Adolescents: A Population-Based Study.Environmental science & technology · 2026Article
- Prenatal Persistent Exposure to Organophosphate Esters and Early Childhood Brain Development: A Longitudinal Analysis.Environment & health (Washington, D.C.) · 2025Article
- Prenatal exposure to organophosphate ester flame retardants and behavioral outcomes in early childhood in the Environmental influences on Child Health Outcomes (ECHO) cohort.Environment international · 2025Article
- Plasma phthalate levels in children with speech delay.Toxicology reports · 2025Article
- Gestational exposure to organophosphate esters and autism spectrum disorder and other non-typical development in a cohort with elevated familial likelihood.Environmental research · 2024Article
- Potential mechanisms and modifications of dietary antioxidants on the associations between co-exposure to plastic additives and diabetes.Nutrition & diabetes · 2024Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPrenatal exposure to phthalates, organophosphate esters, and organophosphorous pesticides have been associated with neurodevelopmental deficits including language ability, however, few studies consider the effect of exposure mixtures and the potential longitudinal detriments over time.
objectiveThis study examines the influence of prenatal exposure to phthalates, organophosphate esters, and organophosphorous pesticides, on children's language ability from toddlerhood to the preschool period.
methodsThis study includes 299 mother-child dyads from Norway in the Norwegian Mother, Father and Child Cohort Study (MoBa). Prenatal exposure to chemicals were assessed at 17 weeks' gestation, and child language skills were assessed at 18 months using the Ages and Stages Questionnaire communication subscale and at preschool age using the Child Development Inventory. We ran two structural equation models to examine the simultaneous influences of chemical exposures on parent-reported and teacher-reported child language ability.
resultsPrenatal organophosphorous pesticides were negatively associated with preschool language ability through language ability at 18 months. Additionally, there was a negative association between low molecular weight phthalates and teacher-reported preschool language ability. There was no effect of prenatal organophosphate esters on child language ability at either 18 months or preschool age.
conclusionsThis study adds to the literature on prenatal exposure to chemicals and neurodevelopment and highlights the importance of developmental pathways in early childhood.
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Registered trials
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