Evidence map›Paper›PMID 36812698›Full record

GuidelinePediatric neurology2023

Consensus-Based Evaluation of Outcome Measures in Pediatric Stroke Care: A Toolkit.

Samantha J Feldman, Lauren A Beslow, Ryan J Felling, Laura A Malone, Michaela Waak, Stuart Fraser, Nihal Bakeer, Jo Ellen M Lee, Victoria Sherman, Melissa M Howard and 3 more

Open access · greenAbstract readPractice GuidelineReview
In one paragraph

Guideline in Pediatric neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Observational
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 3 countries.

Samantha J FeldmanDepartment of Psychology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Lauren A BeslowDivision of Neurology, Children's Hospital of Philadelphia, Departments of Neurology and Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Ryan J FellingDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Laura A MaloneJohns Hopkins University School of Medicine and the Kennedy Krieger Institute, Baltimore, Maryland.
Michaela WaakPediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Queensland, Australia; Pediatric Intensive Care Unit, Queensland Children's Hospital, South Brisbane, Australia.
Stuart FraserDivision of Vascular Neurology, Department of Pediatrics, University of Texas Health Science Center, Houston, Texas.
Nihal BakeerIndiana Hemophilia and Thrombosis Center, Indianapolis, Indiana.
Jo Ellen M LeeDepartment of Neurology, Nationwide Children's Hospital, Columbus, Ohio.
Victoria ShermanSt. Mary's General Hospital, Guelph, Ontario, Canada.
Melissa M HowardCasa Colina Hospital and Centers for Healthcare, Pomona, California.
Beth Anne CavanaughDivision of Pediatric Neurology, Department of Pediatrics, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, Tennessee.
Robyn WestmacottDepartment of Psychology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Lori C JordanDivision of Pediatric Neurology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: lori.jordan@vumc.org.
Hospital for Sick Children · CACasa Colina Centers for Rehabilitation · USChildren's Hospital of Philadelphia · USGuelph General Hospital · CAIndiana Hemophilia and Thrombosis Center · USJohns Hopkins University · USKennedy Krieger Institute · USNationwide Children's Hospital · USThe University of Queensland · AUThe University of Texas Health Science Center at Houston · USUniversity of Tennessee Health Science Center · USVanderbilt University Medical Center · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Research Training of Anesthesiology Physician-ScientistsT32GM135118 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Holger K. Eltzschig, Cynthia Ju · 2022 to 2026
$1.1M
Mentoring in Patient-Oriented Research focused on Neurological Complications of Sickle Cell DiseaseK24HL147017 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JORDAN, LORI CHAFFIN · 2019 to 2023
$547k
NHLBI NIH HHS K24 HL147017NIGMS NIH HHS T32 GM135118
6 · The paper itself

Abstract

Following a pediatric stroke, outcome measures selected for monitoring functional recovery and development vary widely. We sought to develop a toolkit of outcome measures that are currently available to clinicians, possess strong psychometric properties, and are feasible for use within clinical settings. A multidisciplinary group of clinicians and scientists from the International Pediatric Stroke Organization comprehensively reviewed the quality of measures in multiple domains described in pediatric stroke populations including global performance, motor and cognitive function, language, quality of life, and behavior and adaptive functioning. The quality of each measure was evaluated using guidelines focused on responsiveness and sensitivity, reliability, validity, feasibility, and predictive utility. A total of 48 outcome measures were included and were rated by experts based on the available evidence within the literature supporting the strengths of their psychometric properties and practical use. Only three measures were found to be validated for use in pediatric stroke: the Pediatric Stroke Outcome Measure, the Pediatric Stroke Recurrence and Recovery Questionnaire, and the Pediatric Stroke Quality of Life Measure. However, multiple additional measures were deemed to have good psychometric properties and acceptable utility for assessing pediatric stroke outcomes. Strengths and weaknesses of commonly used measures including feasibility are highlighted to guide evidence-based and practicable outcome measure selection. Improving the coherence of outcome assessment will facilitate comparison of studies and enhance research and clinical care in children with stroke. Further work is urgently needed to close the gap and validate measures across all clinically significant domains in the pediatric stroke population.

Indexed as

Outcome Assessment, Health CareQuality of LifeStrokeChildConsensusHumansPsychometricsReproducibility of ResultsAssessmentMeasurementOutcomesPediatric stroke

Identifiers

PMID36812698
PMCPMC10042484
OpenAlexW4317473784

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.