Evidence map›Paper›PMID 36812561›Full record

ArticlePLOS digital health2022

Diagnostic accuracy of handheld fundus photography: A comparative study of three commercially available cameras.

Louisa Lu, Somsanguan Ausayakhun, Sakarin Ausayakuhn, Preeyanuch Khunsongkiet, Atitaya Apivatthakakul, Catherine Q Sun, Tyson N Kim, Michele Lee, Edmund Tsui, Plern Sutra and 1 more

Open access · goldAbstract read
In one paragraph

Article in PLOS digital health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  3. Mobile Diagnostic Clinics.ACS sensors · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Louisa LuFrancis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0002-5575-7495
Somsanguan AusayakhunDepartment of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Sakarin AusayakuhnSriphat Medical Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Preeyanuch KhunsongkietSriphat Medical Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.ORCID https://orcid.org/0000-0003-0053-0370
Atitaya ApivatthakakulDepartment of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.ORCID https://orcid.org/0000-0002-4397-8688
Catherine Q SunFrancis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America.
Tyson N KimDepartment of Ophthalmology, University of California, San Francisco, San Francisco, California, United States of America.
Michele LeeDepartment of Ophthalmology, University of Washington, Seattle, Washington, United States of America.ORCID https://orcid.org/0000-0003-4772-1908
Edmund TsuiFrancis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0001-7532-9191
Plern SutraFrancis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America.
Jeremy D KeenanFrancis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0002-7118-1457
University of California, San Francisco · USChiang Mai University · THUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to compare the sensitivity and specificity of handheld fundus cameras in detecting diabetic retinopathy (DR), diabetic macular edema (DME), and macular degeneration. Participants in the study, conducted at Maharaj Nakorn Hospital in Northern Thailand between September 2018 and May 2019, underwent an ophthalmologist examination as well as mydriatic fundus photography with three handheld fundus cameras (iNview, Peek Retina, Pictor Plus). Photographs were graded and adjudicated by masked ophthalmologists. Outcome measures included the sensitivity and specificity of each fundus camera for detecting DR, DME, and macular degeneration, relative to ophthalmologist examination. Fundus photographs of 355 eyes from 185 participants were captured with each of the three retinal cameras. Of the 355 eyes, 102 had DR, 71 had DME, and 89 had macular degeneration on ophthalmologist examination. The Pictor Plus was the most sensitive camera for each of the diseases (73-77%) and also achieved relatively high specificity (77-91%). The Peek Retina was the most specific (96-99%), although in part due to its low sensitivity (6-18%). The iNview had slightly lower estimates of sensitivity (55-72%) and specificity (86-90%) compared to the Pictor Plus. These findings demonstrated that the handheld cameras achieved high specificity but variable sensitivities in detecting DR, DME, and macular degeneration. The Pictor Plus, iNview, and Peek Retina would have distinct advantages and disadvantages when applied for utilization in tele-ophthalmology retinal screening programs.

Identifiers

PMID36812561
PMCPMC9931246
OpenAlexW4307934925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.